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The lessons of QUANTEC: recommendations for reporting and gathering data on dose-volume dependencies of treatment outcome.QUANTEC 经验教训：关于报告和收集与治疗结果的剂量-体积依赖性相关数据的建议。
Int J Radiat Oncol Biol Phys. 2010 Mar 1;76(3 Suppl):S155-60. doi: 10.1016/j.ijrobp.2009.08.074.
2
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Pelvic Complications After Prostate Cancer Radiation Therapy and Their Management: An International Collaborative Narrative Review.前列腺癌放射治疗后的盆腔并发症及其处理：国际协作叙事性综述。
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本文引用的文献

1
Analysis of radiation pneumonitis risk using a generalized Lyman model.使用广义莱曼模型分析放射性肺炎风险。
Int J Radiat Oncol Biol Phys. 2008 Oct 1;72(2):568-74. doi: 10.1016/j.ijrobp.2008.04.053.
2
A nomogram to predict radiation pneumonitis, derived from a combined analysis of RTOG 9311 and institutional data.一个用于预测放射性肺炎的列线图，源自对RTOG 9311和机构数据的综合分析。
Int J Radiat Oncol Biol Phys. 2007 Nov 15;69(4):985-92. doi: 10.1016/j.ijrobp.2007.04.077. Epub 2007 Aug 6.
3
The atlas of complication incidence: a proposal for a new standard for reporting the results of radiotherapy protocols.并发症发生率图谱：关于放射治疗方案结果报告新标准的提案。
Semin Radiat Oncol. 2006 Oct;16(4):260-8. doi: 10.1016/j.semradonc.2006.04.009.
4
Dose-volume modeling of the risk of postoperative pulmonary complications among esophageal cancer patients treated with concurrent chemoradiotherapy followed by surgery.同步放化疗后手术治疗的食管癌患者术后肺部并发症风险的剂量-体积建模
Int J Radiat Oncol Biol Phys. 2006 Nov 1;66(3):754-61. doi: 10.1016/j.ijrobp.2006.06.002. Epub 2006 Sep 11.
5
Final toxicity results of a radiation-dose escalation study in patients with non-small-cell lung cancer (NSCLC): predictors for radiation pneumonitis and fibrosis.非小细胞肺癌（NSCLC）患者放射剂量递增研究的最终毒性结果：放射性肺炎和肺纤维化的预测因素
Int J Radiat Oncol Biol Phys. 2006 Jul 15;65(4):1075-86. doi: 10.1016/j.ijrobp.2006.01.051. Epub 2006 May 2.
6
Modeling radiation pneumonitis risk with clinical, dosimetric, and spatial parameters.利用临床、剂量学和空间参数对放射性肺炎风险进行建模。
Int J Radiat Oncol Biol Phys. 2006 May 1;65(1):112-24. doi: 10.1016/j.ijrobp.2005.11.046.
7
Sparing of the submandibular glands by intensity modulated radiotherapy in the treatment of head and neck cancer.调强放射治疗在头颈部癌治疗中对下颌下腺的保护作用
Radiother Oncol. 2006 Mar;78(3):270-5. doi: 10.1016/j.radonc.2006.02.017. Epub 2006 Mar 27.
8
Localized volume effects for late rectal and anal toxicity after radiotherapy for prostate cancer.前列腺癌放疗后直肠和肛门晚期毒性的局部容积效应
Int J Radiat Oncol Biol Phys. 2006 Mar 15;64(4):1151-61. doi: 10.1016/j.ijrobp.2005.10.002. Epub 2006 Jan 18.
9
Does radiation dose to the salivary glands and oral cavity predict patient-rated xerostomia and sticky saliva in head and neck cancer patients treated with curative radiotherapy?对头颈部癌患者进行根治性放射治疗时，唾液腺和口腔所接受的辐射剂量能否预测患者自评的口干和唾液黏稠情况？
Radiother Oncol. 2005 Nov;77(2):164-71. doi: 10.1016/j.radonc.2005.10.002. Epub 2005 Oct 26.
10
Statistical analysis of dose-volume and dose-wall histograms for rectal toxicity following 3D-CRT in prostate cancer.前列腺癌三维适形放疗后直肠毒性的剂量体积直方图和剂量-壁直方图的统计分析。
Med Phys. 2005 Aug;32(8):2503-9. doi: 10.1118/1.1951427.

QUANTEC 经验教训：关于报告和收集与治疗结果的剂量-体积依赖性相关数据的建议。

The lessons of QUANTEC: recommendations for reporting and gathering data on dose-volume dependencies of treatment outcome.

机构信息

Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA.

出版信息

Int J Radiat Oncol Biol Phys. 2010 Mar 1;76(3 Suppl):S155-60. doi: 10.1016/j.ijrobp.2009.08.074.

DOI:10.1016/j.ijrobp.2009.08.074
PMID:20171512
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2854159/
Abstract

The 16 clinical articles in this issue review the dose-volume dependence of toxicities of external beam radiotherapy. They are limited by the difficulty of synthesizing results from different publications. The major problems stem from incomplete reporting of results and use of incompatible or ambiguous endpoints. Here we specify these problems; give recommendations to authors, editors, and reviewers on standards of reporting; and provide methods of defining endpoints suitable for the dose-volume analysis of toxicity. Adopting these recommendations will facilitate meta-analysis and increase the utility of individual studies of the dependence of complications on dose distributions.

摘要

本期的 16 篇临床文章回顾了外照射放疗毒性的剂量-体积依赖性。它们受到从不同出版物综合结果的困难所限制。主要问题源于结果报告的不完整和使用不兼容或模糊的终点。在这里，我们具体说明了这些问题；就报告标准向作者、编辑和审稿人提出建议；并提供了适用于毒性剂量-体积分析的终点定义方法。采用这些建议将有助于荟萃分析，并提高对并发症与剂量分布关系的个体研究的实用性。