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昆虫中心粒:一个发现的领域。

The insect centriole: A land of discovery.

机构信息

Department of Evolutionary Biology, University of Siena, Via A. Moro 2, 53100 Siena, Italy.

出版信息

Tissue Cell. 2010 Apr;42(2):69-80. doi: 10.1016/j.tice.2010.01.002. Epub 2010 Feb 19.

Abstract

Centrioles are involved in the formation of cilia and flagella and in the organization of the centrosome, the main microtubule-organizing center of the cell. Since structural and functional centriole aberrations can contribute to several human diseases, these organelles have recently focused the attention of cell biologists. Here, we review data on the insect centrioles, reporting non-canonical aspects of their behaviour, function and architecture. These findings that represent obvious exceptions to the established rule might contribute to advance our understanding in the formation and the function of centrioles.

摘要

中心体参与纤毛和鞭毛的形成,以及细胞中心体的组织,细胞的主要微管组织中心。由于结构和功能的中心体异常可能导致几种人类疾病,这些细胞器最近引起了细胞生物学家的关注。在这里,我们回顾了昆虫中心体的研究数据,报道了它们行为、功能和结构的非典型方面。这些发现是既定规则的明显例外,可能有助于我们深入了解中心体的形成和功能。

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