非法药物使用时间与健康状况之间的关联:来自 2005-2007 年全国药物使用与健康调查的结果。
Associations between duration of illicit drug use and health conditions: results from the 2005-2007 national surveys on drug use and health.
机构信息
Office of Applied Studies, Substance Abuse and Mental Health Services Administration, U.S. Department of Health and Human Services, Rockville, MD 20857, USA.
出版信息
Ann Epidemiol. 2010 Apr;20(4):289-97. doi: 10.1016/j.annepidem.2010.01.003. Epub 2010 Feb 19.
PURPOSE
To estimate and compare prevalence rates of lifetime health conditions by inferred duration of illicit drug use among the general U.S. adult population and to investigate associations between duration of use of each specific illicit drug (marijuana, cocaine, heroin, hallucinogens, or inhalant) and each lifetime health condition after controlling for potential confounding factors.
METHODS
Data from respondents aged 35 to 49 (N = 29,195) from the 2005-2007 National Surveys on Drug Use and Health (NSDUH) were analyzed.
RESULTS
The prevalence rates of a broad range of health conditions by duration of use of specific illicit drug among persons 35 to 49 years of age in the United States were estimated and compared. After adjustment for potential confounding factors, the results of 20 multivariate logistic regression models indicated positive associations between duration of marijuana use and anxiety, depression, sexually transmitted disease (STD), bronchitis, and lung cancer; between duration of cocaine use and anxiety and pancreatitis; between duration of heroin use and anxiety, hepatitis, and tuberculosis; between duration of hallucinogen use and tinnitus and STD; and between duration of inhalant use and anxiety, depression, HIV/AIDS, STD, tuberculosis, bronchitis, asthma, sinusitis, and tinnitus.
CONCLUSIONS
This study provides initial analyses on the relationships between illicit drug use and health conditions based on a large nationally representative sample. These results can help prepare for treating health problems among former and continuing illicit drug users.
目的
估计和比较美国普通成年人群中推断的非法药物使用时间与终生健康状况的流行率,并调查每种特定非法药物(大麻、可卡因、海洛因、迷幻剂或吸入剂)使用时间与每种终生健康状况之间的关联,同时控制潜在的混杂因素。
方法
对 2005-2007 年全国药物使用和健康调查(NSDUH)中年龄在 35 至 49 岁的受访者(N=29195)的数据进行了分析。
结果
对美国 35 至 49 岁人群特定非法药物使用时间与广泛健康状况的流行率进行了估计和比较。在调整潜在混杂因素后,20 个多变量逻辑回归模型的结果表明,大麻使用时间与焦虑、抑郁、性传播疾病(STD)、支气管炎和肺癌之间存在正相关;可卡因使用时间与焦虑和胰腺炎之间存在正相关;海洛因使用时间与焦虑、肝炎和结核病之间存在正相关;迷幻剂使用时间与耳鸣和 STD 之间存在正相关;吸入剂使用时间与焦虑、抑郁、HIV/AIDS、STD、结核病、支气管炎、哮喘、窦炎和耳鸣之间存在正相关。
结论
本研究基于大型全国代表性样本,首次对非法药物使用与健康状况之间的关系进行了分析。这些结果有助于为治疗前和持续使用非法药物者的健康问题做准备。