Department of Gynecology and Obstetrics, Faculty of Medicine, Yeditepe University, and Zeynep Kamil Women’s and Children Disease Education and Research Hospital, Istanbul, Turkey.
Fertil Steril. 2010 Nov;94(6):2312-5. doi: 10.1016/j.fertnstert.2010.01.004. Epub 2010 Feb 20.
To investigate the long-term effects of intestinal vaginoplasty in cases with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome.
Prospective study.
Division of Pelvic Reconstructive Surgery, Department of Gynecology and Obstetrics, at a women's and children disease education and research hospital.
PATIENT(S): Between 2003 and 2009, 29 patients with MRKH syndrome underwent intestinal vaginoplasty.
INTERVENTION(S): Two of the patients were treated with ileal and 27 with sigmoid vaginoplasty.
MAIN OUTCOME MEASURE(S): The age, marital status, associated anomalies, method used for bowel transposition (isoperistaltic/antiperistaltic), type of abdominal incision, and intra- and postoperative complications were evaluated.
RESULT(S): One of the patients for whom ileal vaginoplasty was performed had 40 cm ileal necrosis requiring bilateral ileostomy for 2 months. Introital stenosis was detected in 15 cases (79%) who were unmarried, while none of the married cases had introital stenosis. However, all patients responded to finger-dilatation. All married patients were sexually satisfied after operation. An intraluminal abscess developed in the proximal segment of the neovagina owing to stricture occurring above abdominoperineal tunnel 2 years after operation. In another patient who had a rudimentary uterine horn, hematometra developed 3 years after operation and treated with resection.
CONCLUSION(S): In our experience, sigmoid vaginoplasty seems to be a favorable procedure which provides excellent long-term results for the patients with vaginal agenesis.
探讨肠阴道成形术治疗 Mayer-Rokitansky-Kuster-Hauser(MRKH)综合征的长期效果。
前瞻性研究。
妇女儿童疾病防治与教育研究所妇产科骨盆重建外科。
2003 年至 2009 年,29 例 MRKH 综合征患者接受肠阴道成形术。
2 例患者接受回肠阴道成形术,27 例患者接受乙状结肠阴道成形术。
评估患者年龄、婚姻状况、伴发畸形、肠移位方法(同蠕动/逆蠕动)、腹部切口类型以及术中术后并发症。
1 例回肠阴道成形术患者出现 40cm 回肠坏死,需要行双侧回肠造口术 2 个月。15 例未婚患者(79%)出现入口狭窄,而已婚患者均无入口狭窄。但所有患者均对手指扩张有反应。所有已婚患者术后性生活满意。术后 2 年,因会阴-肛门隧道上方狭窄,导致新阴道近端管腔脓肿。另 1 例患者有残角子宫,术后 3 年发生宫腔积血,行切除术治疗。
根据我们的经验,乙状结肠阴道成形术似乎是一种有利的手术方法,可为阴道发育不全的患者提供良好的长期效果。