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肠阴道成形术:一家三级中心的七年经验。

Intestinal vaginoplasty: seven years' experience of a tertiary center.

机构信息

Department of Gynecology and Obstetrics, Faculty of Medicine, Yeditepe University, and Zeynep Kamil Women’s and Children Disease Education and Research Hospital, Istanbul, Turkey.

出版信息

Fertil Steril. 2010 Nov;94(6):2312-5. doi: 10.1016/j.fertnstert.2010.01.004. Epub 2010 Feb 20.

Abstract

OBJECTIVE

To investigate the long-term effects of intestinal vaginoplasty in cases with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome.

DESIGN

Prospective study.

SETTING

Division of Pelvic Reconstructive Surgery, Department of Gynecology and Obstetrics, at a women's and children disease education and research hospital.

PATIENT(S): Between 2003 and 2009, 29 patients with MRKH syndrome underwent intestinal vaginoplasty.

INTERVENTION(S): Two of the patients were treated with ileal and 27 with sigmoid vaginoplasty.

MAIN OUTCOME MEASURE(S): The age, marital status, associated anomalies, method used for bowel transposition (isoperistaltic/antiperistaltic), type of abdominal incision, and intra- and postoperative complications were evaluated.

RESULT(S): One of the patients for whom ileal vaginoplasty was performed had 40 cm ileal necrosis requiring bilateral ileostomy for 2 months. Introital stenosis was detected in 15 cases (79%) who were unmarried, while none of the married cases had introital stenosis. However, all patients responded to finger-dilatation. All married patients were sexually satisfied after operation. An intraluminal abscess developed in the proximal segment of the neovagina owing to stricture occurring above abdominoperineal tunnel 2 years after operation. In another patient who had a rudimentary uterine horn, hematometra developed 3 years after operation and treated with resection.

CONCLUSION(S): In our experience, sigmoid vaginoplasty seems to be a favorable procedure which provides excellent long-term results for the patients with vaginal agenesis.

摘要

目的

探讨肠阴道成形术治疗 Mayer-Rokitansky-Kuster-Hauser(MRKH)综合征的长期效果。

设计

前瞻性研究。

地点

妇女儿童疾病防治与教育研究所妇产科骨盆重建外科。

患者

2003 年至 2009 年,29 例 MRKH 综合征患者接受肠阴道成形术。

干预措施

2 例患者接受回肠阴道成形术,27 例患者接受乙状结肠阴道成形术。

主要观察指标

评估患者年龄、婚姻状况、伴发畸形、肠移位方法(同蠕动/逆蠕动)、腹部切口类型以及术中术后并发症。

结果

1 例回肠阴道成形术患者出现 40cm 回肠坏死,需要行双侧回肠造口术 2 个月。15 例未婚患者(79%)出现入口狭窄,而已婚患者均无入口狭窄。但所有患者均对手指扩张有反应。所有已婚患者术后性生活满意。术后 2 年,因会阴-肛门隧道上方狭窄,导致新阴道近端管腔脓肿。另 1 例患者有残角子宫,术后 3 年发生宫腔积血,行切除术治疗。

结论

根据我们的经验,乙状结肠阴道成形术似乎是一种有利的手术方法,可为阴道发育不全的患者提供良好的长期效果。

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