Department of Histology and Biology of Reproduction, Tenon Hospital (Assistance Publique Hôpitaux de Paris), Paris, France.
Fertil Steril. 2010 Jul;94(2):753.e1-3. doi: 10.1016/j.fertnstert.2010.01.017. Epub 2010 Feb 20.
To raise the possibility that pregnancy can be obtained by assisted reproductive techniques in patients with human seminal plasma allergy.
Case report.
University hospital.
PATIENT(S): A woman consulted for a 3-year primary infertility. She reported lack of intercourse because of a seminal plasma allergy.
INTERVENTION(S): One intrauterine insemination associated with antihistamine treatment was performed with carefully washed spermatozoa.
RESULT(S): Immediately after the insemination, the patient had an allergic reaction treated by steroids. Fortunately, this single attempt led to a successful pregnancy, and the patient gave birth to a healthy girl.
CONCLUSION(S): Pregnancies can be obtained in patients with seminal plasma hypersensitivity by means of intrauterine insemination. However, serious complications may occur after performing intrauterine insemination, which is not a totally reliable method to prevent an allergic reaction. Thus a multidisciplinary team should follow such patients carefully and watch for the potential risks and side effects. In vitro fertilization may represent the more cautious option.
提出一种可能性，即人类精液过敏的患者可以通过辅助生殖技术怀孕。
病例报告。
大学医院。
一名因精液过敏而无法进行性行为的原发性不孕 3 年的女性前来就诊。
用经过精心清洗的精子进行了一次宫腔内人工授精，并同时给予抗组胺治疗。
授精后，患者立即出现过敏反应，使用类固醇进行治疗。幸运的是，这一次尝试导致了成功怀孕，患者生下了一个健康的女孩。
通过宫腔内人工授精可以使精液过敏患者怀孕。然而，宫腔内人工授精后可能会发生严重并发症，因此并非预防过敏反应的完全可靠方法。因此，应让多学科团队仔细随访此类患者，并注意潜在的风险和副作用。体外受精可能是更谨慎的选择。
