利用无脂管被动采样器和胚胎斑马鱼将特定地点的污染物混合物与生物反应联系起来。
Exploiting lipid-free tubing passive samplers and embryonic zebrafish to link site specific contaminant mixtures to biological responses.
机构信息
Environmental and Molecular Toxicology Department, Oregon State University, ALS 1007, Corvallis, OR 97331, USA.
出版信息
Chemosphere. 2010 Mar;79(1):1-7. doi: 10.1016/j.chemosphere.2010.02.001. Epub 2010 Feb 20.
Abstract
The Biological Response Indicator Devices Gauging Environmental Stressors (BRIDGES) bio-analytical tool was developed in response to the need for a quantitative technology for assessing the toxicity of environmentally relevant contaminant mixtures. This tool combines passive samplers with the embryonic zebrafish model. When applied in an urban river it effectively linked site specific, bioavailable contaminant mixtures to multiple biological responses. Embryonic zebrafish exposed to extracts from lipid-free passive samplers that were deployed at five locations, within and outside of the Portland Harbor Superfund Megasite, displayed different responses. Six of the eighteen biological responses observed in 941 exposed zebrafish were significantly different between sites. This demonstrates the sensitivity of the bio-analytical tool for detecting spatially distinct toxicity in aquatic systems; bridging environmental exposure to biological response.
摘要
生物反应指示设备评估环境胁迫物（BRIDGES）生物分析工具是为了满足评估具有环境相关性的污染物混合物毒性的定量技术需求而开发的。该工具将被动采样器与胚胎斑马鱼模型相结合。当应用于城市河流时，它有效地将特定地点的、生物可利用的污染物混合物与多种生物反应联系起来。暴露于在波特兰港超级基金特大污染区内外五个地点部署的无脂被动采样器提取物中的胚胎斑马鱼表现出不同的反应。在 941 条暴露的斑马鱼中观察到的 18 种生物反应中有 6 种在地点之间存在显著差异。这表明该生物分析工具具有检测水生系统中空间上不同毒性的敏感性，从而将环境暴露与生物反应联系起来。
相似文献
1
Exploiting lipid-free tubing passive samplers and embryonic zebrafish to link site specific contaminant mixtures to biological responses.利用无脂管被动采样器和胚胎斑马鱼将特定地点的污染物混合物与生物反应联系起来。
Chemosphere. 2010 Mar;79(1):1-7. doi: 10.1016/j.chemosphere.2010.02.001. Epub 2010 Feb 20.
2
Bridging environmental mixtures and toxic effects.弥合环境混合物与毒性效应之间的差距。
Environ Toxicol Chem. 2012 Dec;31(12):2877-87. doi: 10.1002/etc.2018. Epub 2012 Nov 7.
3
Using passive sampling and zebrafish to identify developmental toxicants in complex mixtures.利用被动采样和斑马鱼鉴定复杂混合物中的发育毒性剂。
Environ Toxicol Chem. 2017 Sep;36(9):2290-2298. doi: 10.1002/etc.3802. Epub 2017 Apr 17.
4
Toxicity of sediment cores from Yangtze River estuary to zebrafish (Danio rerio) embryos.长江河口沉积物岩芯对斑马鱼（Danio rerio）胚胎的毒性。
Environ Sci Pollut Res Int. 2015 Nov;22(21):16423-33. doi: 10.1007/s11356-014-3484-5. Epub 2014 Aug 28.
5
Toxicity of 10 organic micropollutants and their mixture: Implications for aquatic risk assessment.10 种有机微污染物及其混合物的毒性：对水生风险评估的影响。
Sci Total Environ. 2019 May 20;666:1273-1282. doi: 10.1016/j.scitotenv.2019.02.047. Epub 2019 Feb 15.
6
Evaluations of combined zebrafish (Danio rerio) embryo and marine phytoplankton (Diacronema lutheri) toxicity of dissolved organic contaminants in the Ythan catchment, Scotland, UK.英国苏格兰亚顿流域溶解有机污染物对斑马鱼（Danio rerio）胚胎和海洋浮游植物（Diacronema lutheri）联合毒性的评价。
Environ Sci Pollut Res Int. 2014 Apr;21(8):5537-46. doi: 10.1007/s11356-013-2488-x. Epub 2014 Jan 10.
7
Co-exposure to microplastic and plastic additives causes development impairment in zebrafish embryos.同时接触微塑料和塑料添加剂会导致斑马鱼胚胎发育受损。
Aquat Toxicol. 2024 Aug;273:107001. doi: 10.1016/j.aquatox.2024.107001. Epub 2024 Jun 13.
8
Embryotoxicity and genotoxicity evaluation of sediments from Yangtze River estuary using zebrafish (Danio rerio) embryos.利用斑马鱼（Danio rerio）胚胎对长江河口沉积物进行胚胎毒性和遗传毒性评估。
Environ Sci Pollut Res Int. 2016 Mar;23(5):4908-18. doi: 10.1007/s11356-015-5737-3. Epub 2015 Nov 7.
9
Behavioral profile alterations in zebrafish larvae exposed to environmentally relevant concentrations of eight priority pharmaceuticals.斑马鱼幼鱼暴露于八种优先药物的环境相关浓度下的行为特征改变。
Sci Total Environ. 2019 May 10;664:89-98. doi: 10.1016/j.scitotenv.2019.01.300. Epub 2019 Jan 24.
10
Effect-directed analysis of Elizabeth River porewater: developmental toxicity in zebrafish (Danio rerio).伊丽莎白河孔隙水的效应导向分析：斑马鱼（Danio rerio）的发育毒性
Environ Toxicol Chem. 2014 Dec;33(12):2767-74. doi: 10.1002/etc.2738.
引用本文的文献
1
A novel multitask learning algorithm for tasks with distinct chemical space: zebrafish toxicity prediction as an example.一种用于具有不同化学空间任务的新型多任务学习算法：以斑马鱼毒性预测为例。
J Cheminform. 2024 Aug 2;16(1):91. doi: 10.1186/s13321-024-00891-4.
2
Coupling Environmental Whole Mixture Toxicity Screening with Unbiased RNA-Seq Reveals Site-Specific Biological Responses in Zebrafish.将环境全混合物毒性筛选与无偏RNA测序相结合揭示斑马鱼的位点特异性生物学反应。
Toxics. 2023 Feb 21;11(3):201. doi: 10.3390/toxics11030201.
3
The Superfund Research Program Analytics Portal: linking environmental chemical exposure to biological phenotypes.超级基金研究计划分析门户：将环境化学暴露与生物表型联系起来。
Sci Data. 2023 Mar 21;10(1):151. doi: 10.1038/s41597-023-02021-5.
4
Predicting polycyclic aromatic hydrocarbon concentrations in resident aquatic organisms using passive samplers and partial least-squares calibration.利用被动采样器和偏最小二乘法校准来预测居民水生生物体内多环芳烃浓度。
Environ Sci Technol. 2014 Jun 3;48(11):6291-9. doi: 10.1021/es5000534. Epub 2014 May 19.
5
The influences of parental diet and vitamin E intake on the embryonic zebrafish transcriptome.父母饮食和维生素 E 摄入对胚胎斑马鱼转录组的影响。
Comp Biochem Physiol Part D Genomics Proteomics. 2014 Jun;10:22-9. doi: 10.1016/j.cbd.2014.02.001. Epub 2014 Mar 1.
6
Passive sampling coupled to ultraviolet irradiation: a useful analytical approach for studying oxygenated polycyclic aromatic hydrocarbon formation in bioavailable mixtures.被动采样结合紫外辐射：一种研究生物可利用混合物中含氧多环芳烃形成的有用分析方法。
Environ Toxicol Chem. 2014 Jan;33(1):177-81. doi: 10.1002/etc.2410. Epub 2013 Nov 15.
7
Bridging environmental mixtures and toxic effects.弥合环境混合物与毒性效应之间的差距。
Environ Toxicol Chem. 2012 Dec;31(12):2877-87. doi: 10.1002/etc.2018. Epub 2012 Nov 7.
8
Alternate glucocorticoid receptor ligand binding structures influence outcomes in an in vivo tissue regeneration model.替代糖皮质激素受体配体结合结构影响体内组织再生模型的结果。
Comp Biochem Physiol C Toxicol Pharmacol. 2012 Aug;156(2):121-9. doi: 10.1016/j.cbpc.2012.05.003. Epub 2012 May 24.
本文引用的文献
1
Spatial and temporal variation of freely dissolved polycyclic aromatic hydrocarbons in an urban river undergoing Superfund remediation.一条正在进行超级基金修复的城市河流中自由溶解的多环芳烃的时空变化。
Environ Sci Technol. 2008 Dec 15;42(24):9065-71. doi: 10.1021/es801286z.
2
A "toolbox" for biological and chemical monitoring requirements for the European Union's Water Framework Directive.欧盟水框架指令生物和化学监测要求的“工具箱”
Talanta. 2006 Apr 15;69(2):302-22. doi: 10.1016/j.talanta.2005.09.043. Epub 2005 Nov 15.
3
A tale of two fish.两条鱼的故事。
Environ Sci Technol. 2008 Sep 15;42(18):6784-5. doi: 10.1021/es801813m.
4
Semipermeable membrane devices link site-specific contaminants to effects: Part 1 - Induction of CYP1A in rainbow trout from contaminants in Prince William Sound, Alaska.半透膜装置将特定地点的污染物与影响联系起来：第1部分 - 阿拉斯加威廉王子湾的污染物对虹鳟鱼CYP1A的诱导作用
Mar Environ Res. 2008 Dec;66(5):477-86. doi: 10.1016/j.marenvres.2008.07.001. Epub 2008 Jul 8.
5
In vivo evaluation of carbon fullerene toxicity using embryonic zebrafish.利用斑马鱼胚胎进行碳富勒烯毒性的体内评估。
Carbon N Y. 2007 Aug;45(9):1891-1898. doi: 10.1016/j.carbon.2007.04.021.
6
Field trial and modeling of uptake rates of in situ lipid-free polyethylene membrane passive sampler.原位无脂聚乙烯膜被动采样器摄取率的现场试验与建模
Environ Sci Technol. 2008 Jun 15;42(12):4486-93. doi: 10.1021/es702657n.
7
Cumulative risk assessment of pesticide residues in food.食品中农药残留的累积风险评估。
Toxicol Lett. 2008 Aug 15;180(2):137-50. doi: 10.1016/j.toxlet.2008.06.004. Epub 2008 Jun 8.
8
Developmental toxicity and alteration of gene expression in zebrafish embryos exposed to PFOS.全氟辛烷磺酸暴露下斑马鱼胚胎的发育毒性及基因表达变化
Toxicol Appl Pharmacol. 2008 Jul 1;230(1):23-32. doi: 10.1016/j.taap.2008.01.043. Epub 2008 Feb 20.
9
Individual and joint toxic effects of pentachlorophenol and bisphenol A on the development of zebrafish (Danio rerio) embryo.五氯苯酚和双酚 A 对斑马鱼 (Danio rerio) 胚胎发育的单独及联合毒性作用。
Ecotoxicol Environ Saf. 2008 Nov;71(3):774-80. doi: 10.1016/j.ecoenv.2008.01.021. Epub 2008 Mar 21.
10
Toxicology. Transforming environmental health protection.毒理学。转变环境卫生保护。
Science. 2008 Feb 15;319(5865):906-7. doi: 10.1126/science.1154619.
Zotero 插件