Jimenez Nathalia, Seidel Kristy, Martin Lynn D, Rivara Frederick P, Lynn Anne M
Department of Anesthesiology and Pain Medicine, Seattle Children's Hospital, 4800 Sand Point Way NE, Seattle, WA 98105, USA.
J Health Care Poor Underserved. 2010 Feb;21(1):229-36. doi: 10.1353/hpu.0.0236.
Adult studies suggest pain treatment is influenced by patient's race/ ethnicity. The present study aims to evaluate the effect of the patient's race/ethnicity on pain treatment in children.
Retrospective cohort study comparing perioperative analgesic administration for tonsillectomy and adenoidectomy (T&A) surgery in Latino and Caucasian patients younger than 18 years of age.
Ninety-four (94) patients were included (47 Latino, 47 Caucasian), mean age 8.44 yrs (SD 3.45), 43% female. Administration of non-opioid analgesics and intraoperative opioids was similar in both groups. Early post-operative administration of opioid analgesics was significantly different between groups. Latino subjects received 30% less opioid analgesics than Caucasians; median amount in morphine equivalents was 0.05 (0-0.14) vs. 0.07 (0-0.90) mg/kg for Latino and Caucasian patients respectively (p5.02).
This study suggests that perioperative pain treatment in children is correlated with the patient's ethnicity. The cause of this difference is unknown and prospective studies are necessary to elucidate the reasons.
成人研究表明疼痛治疗受患者种族/民族的影响。本研究旨在评估患者种族/民族对儿童疼痛治疗的影响。
回顾性队列研究，比较18岁以下拉丁裔和白种人患者扁桃体切除术和腺样体切除术（T&A）围手术期的镇痛药物使用情况。
纳入94例患者（47例拉丁裔，47例白种人），平均年龄8.44岁（标准差3.45），43%为女性。两组非阿片类镇痛药和术中阿片类药物的使用情况相似。两组术后早期阿片类镇痛药的使用存在显著差异。拉丁裔受试者接受的阿片类镇痛药比白种人少30%；拉丁裔和白种人患者吗啡当量的中位数分别为0.05（0 - 0.14）和0.07（0 - 0.90）mg/kg（p = 0.02）。
本研究表明儿童围手术期疼痛治疗与患者种族有关。这种差异的原因尚不清楚，需要进行前瞻性研究以阐明原因。
