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[房水中非甾体类抗炎局部用药的浓度]

[Concentration of non-steroidal, anti-inflammatory topical agents in the aqueous humor].

作者信息

Strobel J

机构信息

Universitäts-Augenklinik Giessen.

出版信息

Ophthalmologica. 1991;202(1):38-42. doi: 10.1159/000310167.

DOI:10.1159/000310167
PMID:2017331
Abstract

In a prospective randomised study we tested two non-steroidal anti-inflammatory medications clinically in a group of 40 eyes. 20 eyes received topically administered indomethacin and another 20 flurbiprofen eyedrops. Before we started the planned extracapsular cataract extraction we performed a puncture of the anterior chamber and aspirated a small volume of anterior chamber fluid. We examined the concentrations of the applied drugs in the aspirated volume. The concentration of indomethacin is 7-9 times higher than that of flurbiprofen.

摘要

在一项前瞻性随机研究中,我们对一组40只眼进行了两种非甾体抗炎药物的临床测试。20只眼接受局部应用吲哚美辛,另外20只眼接受氟比洛芬滴眼液。在开始计划的白内障囊外摘除术前,我们进行了前房穿刺并抽取了少量前房液。我们检测了抽取液中所用药物的浓度。吲哚美辛的浓度比氟比洛芬高7至9倍。

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