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用于一微米光源的自适应光学视网膜扫描仪。

Adaptive optics retinal scanner for one-micrometer light source.

作者信息

Kurokawa Kazuhiro, Tamada Daiki, Makita Shuichi, Yasuno Yoshiaki

机构信息

Computational Optics Group in the University of Tsukuba, Tsukbua, Ibaraki, Japan.

出版信息

Opt Express. 2010 Jan 18;18(2):1406-18. doi: 10.1364/OE.18.001406.

DOI:10.1364/OE.18.001406
PMID:20173968
Abstract

We developed an adaptive optics (AO) retinal scanner by using a light source with a center wavelength of 1-microm. In a recent study on optical coherence tomography (OCT), it was proved that 1-microm light provided higher image contrast of deep region of the eye than 840-nm light. Further, high lateral resolution retinal images were obtained with AO. In this study, we performed measurements on two normal subjects in the AO-SLO mode and analyzed its performance toward developing the AO-OCT. With AO correction, we found that the residual RMS wavefront error of ocular aberration was less than 0.1 microm. We also found that the AO retinal scanner in the AO-SLO mode enabled enhanced observation of photoreceptor mosaic.

摘要

我们通过使用中心波长为1微米的光源开发了一种自适应光学(AO)视网膜扫描仪。在最近一项关于光学相干断层扫描(OCT)的研究中,已证明1微米的光比840纳米的光在眼部深层区域提供更高的图像对比度。此外,利用AO获得了高横向分辨率的视网膜图像。在本研究中,我们以AO-SLO模式对两名正常受试者进行了测量,并分析了其在开发AO-OCT方面的性能。通过AO校正,我们发现眼部像差的残余均方根波前误差小于0.1微米。我们还发现,处于AO-SLO模式的AO视网膜扫描仪能够增强对视锥细胞镶嵌的观察。

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1
Adaptive optics retinal scanner for one-micrometer light source.用于一微米光源的自适应光学视网膜扫描仪。
Opt Express. 2010 Jan 18;18(2):1406-18. doi: 10.1364/OE.18.001406.
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A dual-modal retinal imaging system with adaptive optics.一种具有自适应光学的双模态视网膜成像系统。
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High-resolution retinal imaging through open-loop adaptive optics.基于开环自适应光学的高分辨率视网膜成像。
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Simultaneous dual-band optical coherence tomography in the spectral domain for high resolution in vivo imaging.用于高分辨率体内成像的光谱域同步双波段光学相干断层扫描技术。
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Adaptive optics-optical coherence tomography: optimizing visualization of microscopic retinal structures in three dimensions.自适应光学-光学相干断层扫描:优化三维微观视网膜结构的可视化
J Opt Soc Am A Opt Image Sci Vis. 2007 May;24(5):1373-83. doi: 10.1364/josaa.24.001373.
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High-resolution, in vivo retinal imaging using adaptive optics and its future role in ophthalmology.使用自适应光学的高分辨率活体视网膜成像及其在眼科中的未来作用。
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