Ramirez-Fort Marigdalia K, Khan Farhan, Rosendahl Cliff O, Mercer Stephen E, Shim-Chang Helen, Levitt Jacob O
Center for Clinical Studies, 1401 Binz St., Houston, TX 77004, USA.
Dermatol Online J. 2013 Jul 14;19(7):18958.
Acquired Perforating Dermatosis (APD) is a perforating disease characterized by transepidermal elimination of dermal material [1,2]. This disease usually develops in adulthood. APD has been reported to occur in association with various diseases, but is most commonly associated with dialysis-dependent chronic renal failure (CRF) or diabetes mellitus (DM) [1,2,3,4]. Morton et al found that APD occurs in up to 10% of patients undergoing hemodialysis [5]. Additionally, Saray et al found that sixteen of twenty-two cases with APD were associated with CRF [3].
获得性穿通性皮肤病（APD）是一种以真皮物质经表皮排出为特征的穿通性疾病[1,2]。这种疾病通常在成年期发病。据报道，APD与多种疾病相关，但最常见的是与依赖透析的慢性肾衰竭（CRF）或糖尿病（DM）相关[1,2,3,4]。莫顿等人发现，接受血液透析的患者中高达10%会发生APD[5]。此外，萨雷等人发现，22例APD病例中有16例与CRF相关[3]。
