Unit of Cancer Epidemiology/Belgian Cancer Center, Scientific Institute of Public Health, Brussels, Belgium.
Mass Screening Registry, Finnish Cancer Registry, Helsinki, Finland.
Ann Oncol. 2010 Mar;21(3):448-458. doi: 10.1093/annonc/mdp471.
European Guidelines for Quality Assurance in Cervical Cancer Screening have been initiated in the Europe Against Cancer Programme. The first edition established the principles of organised population-based screening and stimulated numerous pilot projects. The second multidisciplinary edition was published in 2008 and comprises approximately 250 pages divided into seven chapters prepared by 48 authors and contributors. Considerable attention has been devoted to organised, population-based programme policies which minimise adverse effects and maximise benefits of screening. It is hoped that this expanded guidelines edition will have a greater impact on countries in which screening programmes are still lacking and in which opportunistic screening has been preferred in the past. Other methodological aspects such as future prospects of human papillomavirus testing and vaccination in cervical cancer control have also been examined in the second edition; recommendations for integration of the latter technologies into European guidelines are currently under development in a related project supported by the European Union Health Programme. An overview of the fundamental points and principles that should support any quality-assured screening programme and key performance indicators are presented here in a summary document of the second guidelines edition in order to make these principles and standards known to a wider scientific community.
欧洲癌症防治规划发起了《宫颈癌筛查质量保证欧洲指南》。第一版确定了有组织的基于人群的筛查原则,并激发了众多试点项目。第二版多学科指南于 2008 年出版,共有约 250 页,分为七个章节,由 48 位作者和撰稿人编写。本指南还特别关注有组织的基于人群的项目政策,以尽量减少筛查的不良影响,最大程度地提高筛查的效益。希望这一扩展版指南能对那些仍缺乏筛查项目且过去偏好机会性筛查的国家产生更大的影响。第二版还审查了其他方法学方面的内容,如人乳头瘤病毒检测和宫颈癌控制疫苗接种的未来前景;目前正在欧盟卫生规划相关项目的支持下制定将后者技术纳入欧洲指南的建议。本文件是第二版指南的总结文件,概述了任何有质量保证的筛查计划都应遵循的基本原则和关键绩效指标,以向更广泛的科学界介绍这些原则和标准。