Bayrak Sule, Tunc Emine Sen, Sonmez Isil Saroglu, Egilmez Turkan, Ozmen Bilal
Department of Pediatric Dentistry, Faculty of Dentistry, Ondokuz Mayis University, 55139 Samsun, Turkey.
Am J Dent. 2009 Dec;22(6):393-6.
To evaluate the effect of casein phosphopeptide-amorphous calcium phosphate (CCP-ACP) application on the microhardness of bleached enamel and compare it to that of fluoride application.
10 extracted bovine incisors were cut into four sections (4 x 4 x 3 mm) that were randomly distributed among five groups (n = 8). All groups were bleached three times using 38% hydrogen peroxide (HP), with 5-day intervals between bleaching, according to the following treatment protocols: Group A: bleaching only; Group B: bleaching + daily CCP-ACP paste; Group C: bleaching + daily casein phosphopeptide-amorphous calcium fluoride phosphate (CPP-ACPF) paste; Group D: bleaching + daily 250ppm NaF solution; Group E: bleaching + APF gel (once after final bleaching). Specimens were maintained in artificial saliva throughout the experiment. Baseline and post-treatment Vickers microhardness values were obtained for all specimens. Statistical analysis was performed using one-way ANOVA and post-hoc Tukey tests.
Groups B and C showed significant increases in enamel microhardness following treatment (P < 0.001), whereas no statistically significant changes were observed in Groups A, D, or E (P > 0.05). One-way ANOVA of delta Vickers microhardness numbers (deltaVHN) revealed significant differences among groups (P < 0.001), with Group B showing the highest deltaVHN and Group A the lowest.
评估酪蛋白磷酸肽-无定形磷酸钙（CCP-ACP）应用于漂白牙釉质微硬度的效果，并与氟化物应用的效果进行比较。
将10颗拔除的牛切牙切成四段（4×4×3毫米），随机分为五组（n = 8）。根据以下治疗方案，所有组均使用38%过氧化氢（HP）进行三次漂白，每次漂白间隔5天：A组：仅漂白；B组：漂白+每日使用CCP-ACP糊剂；C组：漂白+每日使用酪蛋白磷酸肽-无定形氟磷酸钙（CPP-ACPF）糊剂；D组：漂白+每日使用250ppm氟化钠溶液；E组：漂白+APF凝胶（在最后一次漂白后使用一次）。在整个实验过程中，标本保存在人工唾液中。获取所有标本的基线和治疗后的维氏微硬度值。使用单因素方差分析和事后Tukey检验进行统计分析。
治疗后，B组和C组牙釉质微硬度显著增加（P < 0.001），而A组、D组或E组未观察到统计学上的显著变化（P > 0.05）。维氏微硬度变化值（deltaVHN）的单因素方差分析显示组间存在显著差异（P < 0.001），B组的deltaVHN最高，A组最低。
