Jilani Ghorbel, Mohamed Dridi, Wadia Hellara, Ramzi Khiari, Meriem Jones, Houssem Laarbi, Samir Ghozzi, Nawfel Ben Raies
Urology Department, Militairy Hospital of Tunis, 1008, Monfleury, Tunis, Tunisia.
Dermatol Online J. 2010 Feb 15;16(2):10.
A 39-year-old man, who had undergone left nephrectomy for renal cell carcinoma of clear cell type, was noted to have a solitary nodular shadow in the right lung on chest X-ray. Percutaneous needle biopsy of the lung was performed via the right anterior chest wall and the histologic findings showed metastasis from renal carcinoma. Six month later, the patient presented with a cutaneous nodule at the site of puncture of the lung needle biopsy. Histological examination of a biopsy of the skin tumor revealed features of metastatic renal cell carcinoma of clear cell type. Surgical excision of the cutaneous nodule was performed, followed by radiotherapy at the site of the skin lesion on the chest wall. After treatment, the patient remains disease free after one year of follow-up. This case represents an unusual clinical presentation of metastatic renal cell carcinoma that appears to have been translocated to the skin by the needle biopsy.
一名39岁男性，因透明细胞型肾细胞癌接受了左肾切除术，胸部X线检查发现右肺有一个孤立的结节状阴影。通过右前胸壁对肺部进行经皮穿刺活检，组织学检查结果显示为肾癌转移。6个月后，患者在肺穿刺活检部位出现一个皮肤结节。对皮肤肿瘤活检的组织学检查显示为透明细胞型转移性肾细胞癌的特征。对皮肤结节进行了手术切除，随后对胸壁皮肤病变部位进行了放射治疗。治疗后，经过一年的随访，患者无疾病复发。该病例代表了转移性肾细胞癌一种不寻常的临床表现，似乎是通过穿刺活检转移至皮肤的。
