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肾细胞癌胸腔活检后肿瘤种植:一例病例报告及文献综述

Tumour Seeding After a Thoracic Biopsy for Renal Cell Carcinoma: A Case Report and a Review of the Literature.

作者信息

Michele Dionese, Umberto Basso, Gaetano Ramondo, Francesco Pierantoni, Davide Bimbatti, Francesca Caumo, Zagone Vittorina, Marco Maruzzo

机构信息

Oncology Unit 1, Istituto Oncologico Veneto IOV-IRCCS, Padua, Italy.

Department of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy.

出版信息

Clin Med Insights Oncol. 2021 Jun 18;15:11795549211022261. doi: 10.1177/11795549211022261. eCollection 2021.

DOI:10.1177/11795549211022261
PMID:34211307
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8216389/
Abstract

The role of percutaneous tumour biopsies had gain importance in the management of renal cell carcinoma to provide diagnostic specimen for the patients with metastatic disease that could benefit a systemic treatment. Among the possible complications of this procedure, however, there is the risk of tumoral cells seeding along the biopsy's tract; this complication, albeit being reported as anecdotal, could have devastating effects. Here we report a case of a young male who developed subcutaneous chest metastasis of renal cell carcinoma after a biopsy of a lung nodule. We subsequently reviewed other cases reported in literature.

摘要

经皮肿瘤活检在肾细胞癌的治疗中发挥着越来越重要的作用,可为转移性疾病患者提供诊断标本,使其有可能从全身治疗中获益。然而,在该操作可能出现的并发症中,存在肿瘤细胞沿活检通道播散的风险;这种并发症尽管报道较少,但可能产生毁灭性影响。在此,我们报告一例年轻男性患者,在肺结节活检后发生了肾细胞癌的胸部皮下转移。随后,我们回顾了文献中报道的其他病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/270c/8216389/69ecd2127613/10.1177_11795549211022261-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/270c/8216389/69ecd2127613/10.1177_11795549211022261-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/270c/8216389/69ecd2127613/10.1177_11795549211022261-fig1.jpg

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本文引用的文献

1
Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up†.肾细胞癌:ESMO 诊断、治疗及随访临床实践指南†
Ann Oncol. 2019 May 1;30(5):706-720. doi: 10.1093/annonc/mdz056.
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Immune context characterization and heterogeneity in primary tumors and pulmonary metastases from renal cell carcinoma.肾细胞癌原发肿瘤和肺转移灶的免疫背景特征及异质性。
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Tumour Seeding in the Tract of Percutaneous Renal Tumour Biopsy: A Report on Seven Cases from a UK Tertiary Referral Centre.
机器人辅助肾部分切除术后肾细胞癌的腹膜后播散转移
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经皮肾肿瘤活检过程中的肿瘤种植:英国一家三级转诊中心的 7 例报告。
Eur Urol. 2019 May;75(5):861-867. doi: 10.1016/j.eururo.2018.12.011. Epub 2018 Dec 24.
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Comparison of Immediate vs Deferred Cytoreductive Nephrectomy in Patients With Synchronous Metastatic Renal Cell Carcinoma Receiving Sunitinib: The SURTIME Randomized Clinical Trial.舒尼替尼治疗同步转移性肾细胞癌患者中即刻与延迟细胞减瘤性肾切除术的比较:SURTIME 随机临床试验。
JAMA Oncol. 2019 Feb 1;5(2):164-170. doi: 10.1001/jamaoncol.2018.5543.
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Tumor seeding from a percutaneous renal mass biopsy.经皮肾肿块活检导致的肿瘤播散。
Urol Case Rep. 2018 Nov 15;23:32-33. doi: 10.1016/j.eucr.2018.11.006. eCollection 2019 Mar.
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Association between renal mass biopsy and upstaging to perinephric fat involvement in a contemporary cohort of patients with clinical T1a renal cell carcinoma.当代临床T1a期肾细胞癌患者队列中肾肿物活检与分期上调至肾周脂肪受累之间的关联。
Urol Oncol. 2018 Dec;36(12):527.e13-527.e19. doi: 10.1016/j.urolonc.2018.08.009. Epub 2018 Sep 15.
7
Sunitinib Alone or after Nephrectomy in Metastatic Renal-Cell Carcinoma.舒尼替尼单药治疗或肾细胞癌转移患者肾切除术后的治疗。
N Engl J Med. 2018 Aug 2;379(5):417-427. doi: 10.1056/NEJMoa1803675. Epub 2018 Jun 3.
8
Tumor Seeding With Renal Cell Carcinoma After Renal Biopsy.肾活检后肾细胞癌的肿瘤种植
Urol Case Rep. 2016 Sep 25;9:43-4. doi: 10.1016/j.eucr.2016.08.008. eCollection 2016 Nov.
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Needle tract seeding following percutaneous biopsy of renal cell carcinoma.肾细胞癌经皮活检后的针道种植。
Korean J Urol. 2015 Sep;56(9):666-9. doi: 10.4111/kju.2015.56.9.666. Epub 2015 Sep 2.