Grewal Navanjun S, Wan Derrick C, Roostaeian Jason, Rubayi Salah R
Department of Surgery, Division of Plastic Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Ann Plast Surg. 2010 Mar;64(3):315-7. doi: 10.1097/SAP.0b013e3181a7302a.
Hidradenitis suppurativa is a chronic, recurrent, inflammatory disease of apocrine gland-bearing skin areas. Long-standing low-grade infection and chronic abscess formation result in ulcers, fistulas, and progressive scars. A rare complication is the development of squamous cell carcinoma, known as Marjolin ulcer. We report 3 cases in which squamous cell carcinoma developed despite medical treatments and local excisions. Because of the poor prognosis associated with squamous cell carcinoma, we advocate wide excision of hidradenitis suppurativa lesions when other treatments have failed.
化脓性汗腺炎是一种累及顶泌汗腺皮肤区域的慢性、复发性炎症性疾病。长期的低度感染和慢性脓肿形成会导致溃疡、瘘管和进行性瘢痕。一种罕见的并发症是鳞状细胞癌的发生，即Marjolin溃疡。我们报告3例病例，尽管接受了药物治疗和局部切除，但仍发生了鳞状细胞癌。由于鳞状细胞癌预后较差，我们主张在其他治疗失败时，对化脓性汗腺炎病变进行广泛切除。
