School of Mathematical Sciences, University of Nottingham, Nottingham NG7 2RD, UK.
Nat Rev Cancer. 2010 Mar;10(3):221-30. doi: 10.1038/nrc2808.
This Timeline article charts progress in mathematical modelling of cancer over the past 50 years, highlighting the different theoretical approaches that have been used to dissect the disease and the insights that have arisen. Although most of this research was conducted with little involvement from experimentalists or clinicians, there are signs that the tide is turning and that increasing numbers of those involved in cancer research and mathematical modellers are recognizing that by working together they might more rapidly advance our understanding of cancer and improve its treatment.
这篇时间线文章描绘了过去 50 年来癌症数学建模方面的进展，重点介绍了用于剖析该疾病的不同理论方法以及由此产生的见解。尽管这项研究大多是在很少有实验人员或临床医生参与的情况下进行的，但有迹象表明，这种情况正在发生变化，越来越多的参与癌症研究和数学建模的人员认识到，通过共同努力，他们可能会更快地提高我们对癌症的认识并改善其治疗效果。
