Ecology and Conservation Lab, Institute of Natural Sciences, Massey University, Auckland Campus, Private Bag 102904, North Shore Mail Centre, Auckland, New Zealand.
Arch Virol. 2010 Apr;155(4):613-20. doi: 10.1007/s00705-010-0607-2. Epub 2010 Feb 24.
Psittacine beak and feather disease (PBFD) is a viral disease distributed worldwide with a potentially critical impact on many rare parrots. While efforts have been made to determine its prevalence in wild and captive psittacines, only limited work has been done to document complete genomes of its causative agent, beak and feather disease virus (BFDV). Here, we describe five full genomes of BFDV isolated from wild specimens of an endemic New Zealand parrot, the red-fronted parakeet (Cyanoramphus novaezelandiae). The isolates share >99% nucleotide similarity amongst themselves and approximately 91-92% similarity to BFDV isolates from southern Africa, Europe and Australia. A maximum-likelihood (ML) phylogenetic tree including 42 other full-genome sequences indicated that the five isolates from red-fronted parakeets represent an undescribed genotype of BFDV. These isolates are evolutionarily most closely related to the Cacatuini isolates from Thailand and the Lorinae isolates from Australia in the rep gene ML tree; however, in the cp ML tree, the evolutionary relationship is closer to viruses found in the Psittacini.
虎皮鹦鹉喙羽病（PBFD）是一种分布于世界各地的病毒性疾病，对许多珍稀鹦鹉具有潜在的严重影响。尽管已经努力确定其在野生和圈养鹦鹉中的流行程度，但仅对其病原体——喙羽病病毒（BFDV）的完整基因组进行了有限的研究。在这里，我们描述了从新西兰特有鹦鹉——红额鹦鹉（Cyanoramphus novaezelandiae）的野生标本中分离出的 5 个 BFDV 全基因组。这些分离株彼此之间的核苷酸相似度>99%，与来自南非、欧洲和澳大利亚的 BFDV 分离株的相似度约为 91-92%。包括 42 个其他全基因组序列的最大似然（ML）系统发育树表明，来自红额鹦鹉的 5 个分离株代表了一种未被描述的 BFDV 基因型。在 rep 基因 ML 树中，这些分离株与来自泰国的 Cacatuini 分离株和来自澳大利亚的 Lorinae 分离株进化上最为密切相关；然而，在 cp ML 树中，与在 Psittacini 中发现的病毒的进化关系更为密切。
