肝癌的外科治疗。
Surgical treatment for liver cancer.
机构信息
Department of Hepatopancreatobiliary Surgery, Division of Surgery, Hammersmith Hospital campus, Imperial College London, Du Cane Road, London W12 0HS, UK.
出版信息
World J Gastroenterol. 2010 Feb 28;16(8):927-33. doi: 10.3748/wjg.v16.i8.927.
Abstract
Primary liver cancer is amongst the commonest tumors worldwide, particularly in parts of the developing world, and is increasing in incidence. Over the past three decades, surgical hepatic resection has evolved from a high risk, resource intensive procedure with limited application, to a safe and commonly performed operation with a range of indications. This article reviews the approach to surgical resection for malignancies such as hepatocellular cancer, metastatic liver deposits and neuroendocrine tumors. Survival data after resection is also reviewed, as well as indications for curative resection.
摘要
原发性肝癌是全球最常见的肿瘤之一，特别是在发展中国家的某些地区，其发病率正在上升。在过去的三十年中，肝切除术已从一种风险高、资源密集且应用范围有限的手术演变为一种安全且广泛应用的手术，适应证也在不断扩大。本文综述了外科手术切除治疗肝细胞癌、肝转移瘤和神经内分泌肿瘤等恶性肿瘤的方法。本文还回顾了切除术后的生存数据以及根治性切除的适应证。
相似文献
1
Surgical treatment for liver cancer.肝癌的外科治疗。
World J Gastroenterol. 2010 Feb 28;16(8):927-33. doi: 10.3748/wjg.v16.i8.927.
2
Hepatic surgery for metastases from neuroendocrine tumors.神经内分泌肿瘤肝转移的肝手术治疗
Surg Oncol Clin N Am. 2003 Jan;12(1):231-42. doi: 10.1016/s1055-3207(02)00076-5.
3
[Diagnosis and treatment of colorectal liver metastases - workflow].[结直肠癌肝转移的诊断与治疗——工作流程]
Zentralbl Chir. 2008 Jun;133(3):267-84. doi: 10.1055/s-2008-1076796.
4
Examining Perioperative Risk Associated with Simultaneous Resection of Primary Neuroendocrine Tumors and Synchronous Hepatic Metastases.探讨原发性神经内分泌肿瘤与同期肝转移灶同期切除的围手术期风险。
World J Surg. 2021 Feb;45(2):531-542. doi: 10.1007/s00268-020-05847-x. Epub 2020 Nov 5.
5
Impact of surgical margin clearance for resection of secondary hepatic malignancies.手术切缘阴性对继发性肝恶性肿瘤切除的影响。
J Surg Oncol. 2016 Mar;113(3):289-95. doi: 10.1002/jso.24107. Epub 2015 Dec 10.
6
One stage curative resection of double intestinal neuroendocrine tumors with thirty-two bilobar liver metastases. A case report.双肠神经内分泌肿瘤伴32个双侧肝转移灶的一期根治性切除。病例报告。
Ann Ital Chir. 2015 Jul-Aug;86(4):317-22.
7
[Principles of curative resection of liver metastases].[肝转移瘤的根治性切除原则]
Chirurg. 1999 Feb;70(2):123-32. doi: 10.1007/pl00002588.
8
[Recurrent liver metastases from colorectal cancer: their surgical treatment].[结直肠癌肝转移复发：其外科治疗]
G Chir. 1999 Jun-Jul;20(6-7):289-92.
9
Liver metastases from colorectal cancer: present surgical approach.结直肠癌肝转移：当前的手术治疗方法
Hepatogastroenterology. 2003 Nov-Dec;50(54):2067-71.
10
Surgical Treatment of Small Bowel Neuroendocrine Tumors.小肠神经内分泌肿瘤的外科治疗
Hematol Oncol Clin North Am. 2016 Feb;30(1):49-61. doi: 10.1016/j.hoc.2015.09.001. Epub 2015 Oct 24.
引用本文的文献
1
Effect of perioperative branched chain amino acids supplementation in liver cancer patients undergoing surgical intervention: A systematic review.围手术期补充支链氨基酸对接受手术干预的肝癌患者的影响：一项系统评价。
World J Gastrointest Surg. 2023 Nov 27;15(11):2596-2618. doi: 10.4240/wjgs.v15.i11.2596.
2
Dose finding study for unilobar radioembolization using holmium-166 microspheres to improve resectability in patients with HCC: the RALLY protocol.钬-166 微球单叶放射性栓塞剂量研究：提高 HCC 患者可切除性的 RALLY 方案。
BMC Cancer. 2023 Aug 18;23(1):771. doi: 10.1186/s12885-023-11280-9.
3
Association Between Socioeconomic and Insurance Status and Delayed Diagnosis of Gastrointestinal Cancers.社会经济地位和保险状况与胃肠道癌延迟诊断的关联。
J Surg Res. 2022 Nov;279:170-186. doi: 10.1016/j.jss.2022.05.027. Epub 2022 Jun 29.
4
Trends and Projections in National United States Health Care Spending for Gastrointestinal Malignancies (1996-2030).美国国家胃肠道恶性肿瘤医疗保健支出的趋势和预测（1996-2030）。
Gastroenterology. 2022 Apr;162(4):1098-1110.e2. doi: 10.1053/j.gastro.2021.12.244. Epub 2021 Dec 16.
5
Cyclin-Dependent Kinase 4 is expected to be a therapeutic target for hepatocellular carcinoma metastasis using integrated bioinformatic analysis.通过综合生物信息学分析，细胞周期蛋白依赖性激酶 4有望成为治疗肝细胞癌转移的靶点。
Bioengineered. 2021 Dec;12(2):11728-11739. doi: 10.1080/21655979.2021.2006942.
6
Grape Seed Proanthocyanidins Induce Apoptosis and Cell Cycle Arrest of HepG2 Cells Accompanied by Induction of the MAPK Pathway and NAG-1.葡萄籽原花青素诱导HepG2细胞凋亡和细胞周期阻滞，并伴随丝裂原活化蛋白激酶（MAPK）通路和NAG-1的诱导。
Antioxidants (Basel). 2020 Nov 28;9(12):1200. doi: 10.3390/antiox9121200.
7
The Potential Gut Microbiota-Mediated Treatment Options for Liver Cancer.肝癌潜在的肠道微生物群介导的治疗选择。
Front Oncol. 2020 Oct 14;10:524205. doi: 10.3389/fonc.2020.524205. eCollection 2020.
8
Effect of co-administration of Bee honey and some chemotherapeutic drugs on dissemination of hepatocellular carcinoma in rats.蜂蜜与某些化疗药物联合使用对大鼠肝细胞癌扩散的影响。
Toxicol Rep. 2019 Aug 16;6:875-888. doi: 10.1016/j.toxrep.2019.08.007. eCollection 2019.
9
DEPTOR induces a partial epithelial-to-mesenchymal transition and metastasis via autocrine TGFβ1 signaling and is associated with poor prognosis in hepatocellular carcinoma.DEPTOR 通过自分泌 TGFβ1 信号诱导部分上皮间质转化和转移，并与肝细胞癌的不良预后相关。
J Exp Clin Cancer Res. 2019 Jun 22;38(1):273. doi: 10.1186/s13046-019-1220-1.
10
The Proanthocyanidin-Rich Fraction Obtained from Red Rice Germ and Bran Extract Induces HepG2 Hepatocellular Carcinoma Cell Apoptosis.红曲米糠提取物中原花青素丰富部分诱导 HepG2 肝癌细胞凋亡。
Molecules. 2019 Feb 23;24(4):813. doi: 10.3390/molecules24040813.
本文引用的文献
1
Liver transplantation versus liver resection for the treatment of hepatocellular carcinoma.肝移植与肝切除术治疗肝细胞癌。
J Surg Oncol. 2010 Jan 1;101(1):47-53. doi: 10.1002/jso.21415.
2
A systematic review on the clinical benefit and role of radiofrequency ablation as treatment of colorectal liver metastases.关于射频消融治疗结直肠癌肝转移的临床益处及作用的系统评价。
Eur J Cancer. 2009 Jul;45(10):1748-56. doi: 10.1016/j.ejca.2009.03.012. Epub 2009 Apr 6.
3
Treatment of liver metastases from neuroendocrine tumours in relation to the extent of hepatic disease.神经内分泌肿瘤肝转移的治疗与肝脏疾病范围的关系。
Br J Surg. 2009 Feb;96(2):175-84. doi: 10.1002/bjs.6468.
4
Hepatectomy for stage B and stage C hepatocellular carcinoma in the Barcelona Clinic Liver Cancer classification: results of a prospective analysis.巴塞罗那临床肝癌分期中B期和C期肝细胞癌的肝切除术：一项前瞻性分析结果
Arch Surg. 2008 Nov;143(11):1082-90. doi: 10.1001/archsurg.143.11.1082.
5
Treatment and prognosis of hepatocellular carcinoma: a population based study in France.肝细胞癌的治疗与预后：法国一项基于人群的研究
J Surg Oncol. 2008 Dec 1;98(7):505-9. doi: 10.1002/jso.21159.
6
Prognostic factors after liver resection for hepatocellular carcinoma with hepatitis B virus-related cirrhosis: surgeon's role in survival.乙型肝炎病毒相关肝硬化肝细胞癌肝切除术后的预后因素：外科医生在生存中的作用
Eur J Surg Oncol. 2009 Jun;35(6):622-8. doi: 10.1016/j.ejso.2008.08.003. Epub 2008 Oct 2.
7
Is hepatic resection justified after chemotherapy in patients with colorectal liver metastases and lymph node involvement?对于伴有淋巴结转移的结直肠癌肝转移患者，化疗后进行肝切除是否合理？
J Clin Oncol. 2008 Aug 1;26(22):3672-80. doi: 10.1200/JCO.2007.15.7297.
8
Surgical technique and systemic inflammation influences long-term disease-free survival following hepatic resection for colorectal metastasis.手术技术和全身炎症影响结直肠癌肝转移切除术后的长期无病生存。
J Surg Oncol. 2008 Oct 1;98(5):371-6. doi: 10.1002/jso.21103.
9
Surgical resection vs. percutaneous ablation for hepatocellular carcinoma: a preliminary report of the Japanese nationwide survey.肝细胞癌的手术切除与经皮消融治疗：日本全国性调查的初步报告
J Hepatol. 2008 Oct;49(4):589-94. doi: 10.1016/j.jhep.2008.05.018. Epub 2008 Jun 12.
10
Prognostic value of concomitant resection of extrahepatic disease in patients with liver metastases of colorectal origin.结直肠癌肝转移患者肝外疾病同期切除的预后价值
Surgery. 2008 Jun;143(6):706-14. doi: 10.1016/j.surg.2008.02.004. Epub 2008 Apr 11.
Zotero 插件