Division of Liver Transplantation, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China.
World J Gastroenterol. 2010 Feb 28;16(8):1039-42. doi: 10.3748/wjg.v16.i8.1039.
Mucormycosis is a rare but invasive opportunistic fungal infection associated with a high mortality rate, and normally occurs in immunocompromised patients. In this report, we describe an immunocompetent patient suffering from hepatic mucormycosis secondary to adrenal mucormycosis, which masquerades as hilar cholangiocarcinoma. After surgical procedure and treatment with amphotericin B and itraconazole, the patient recovered well and had a 2-year infection-free survival. To our knowledge, this special clinical manifestation of hepatic infection as well as adrenal mucormycosis has not been reported to date. Meanwhile, this is the first case of an immunocompetent patient with both adrenal and hepatic mucormycosis who has been treated successfully.
毛霉菌病是一种罕见但具侵袭性的机会性真菌感染，与高死亡率相关，通常发生在免疫功能低下的患者中。在本报告中，我们描述了一例免疫功能正常的患者，继发于肾上腺毛霉菌病的肝毛霉菌病，其表现为肝门部胆管癌。在接受手术和两性霉素 B 及伊曲康唑治疗后，患者恢复良好，感染无复发，生存 2 年。据我们所知，这种肝感染的特殊临床表现以及肾上腺毛霉菌病尚未见报道。同时，这也是首例成功治疗的免疫功能正常的同时患有肾上腺和肝毛霉菌病的患者。
