Bastyr University , School of Naturopathic Medicine, Kenmore, WA, USA.
J Altern Complement Med. 2010 Feb;16(2):165-73. doi: 10.1089/acm.2008.0566.
The objectives of this study were to explore the association between complementary and alternative medicine (CAM) use as reported by youth, and parents' and children's reported quality of life in youth with diabetes.
The study design was a cross-sectional survey.
Youth in Washington State participated in the SEARCH for Diabetes in Youth study, a national, multisite epidemiological study designed to assess the prevalence and incidence of diabetes in U.S. youth. Surveys assessing CAM utilization were mailed in January and April 2006.
One thousand four hundred and thirty-nine (1439) youth were mailed a CAM survey. The final sample consisted of 467 youth with both CAM survey results and quality-of-life data.
Difference in mean scores on Pediatric Quality of Life Inventory (PedsQL) between CAM users and nonusers overall, and specific CAM therapies were the outcome measures.
Of the 1439 participants approached, 587 (40.8%) returned the CAM survey. In adjusted analyses, children reported any CAM use as associated with more barriers to treatment (difference in mean scores -3.48, 95% confidence interval [CI] -6.65, -0.31). Children following a CAM diet reported higher quality of life (PedsQL Core Total difference 4.01, 95% CI [0.10-7.91]; Core Psychosocial difference was 6.45, 95% CI [1.95 to 10.95]), but those using stress-reduction activities reported poorer quality of life (Diabetes Total difference -4.19, 95% CI [-8.35 to -0.04]). Parent-reported quality of life was lower for children who used "other supplements" (Core Total difference -6.26, 95% CI [-11.29 to -1.24]; Core Psychosocial difference was -5.92, 95% CI [-11.65 to -0.19]).
CAM diets were associated with increased quality of life in youth with diabetes, whereas supplement use and stress-reduction activities were associated with decreased quality of life. The temporal sequence between CAM use and quality of life requires further study.
本研究旨在探讨青少年自报的补充和替代医学（CAM）使用情况与糖尿病青少年中父母和儿童自报的生活质量之间的关系。
本研究设计为横断面调查。
华盛顿州的青少年参加了美国 SEARCH for Diabetes in Youth 研究，这是一项全国性的多地点流行病学研究，旨在评估美国青少年中糖尿病的患病率和发病率。2006 年 1 月和 4 月邮寄了评估 CAM 使用情况的调查问卷。
向 1439 名青少年邮寄了 CAM 调查问卷。最终样本包括 467 名同时具有 CAM 调查结果和生活质量数据的青少年。
总体上以及特定 CAM 疗法的使用情况，均以儿童生活质量量表（PedsQL）的平均得分差异作为结局指标。
在被调查的 1439 名参与者中，有 587 名（40.8%）返回了 CAM 调查问卷。在调整后的分析中，儿童自报使用任何 CAM 疗法与治疗障碍增加相关（平均得分差异 -3.48，95%置信区间 [CI] -6.65，-0.31）。采用 CAM 饮食的儿童报告生活质量更高（PedsQL 核心总分差异 4.01，95% CI [0.10-7.91]；核心心理社会差异为 6.45，95% CI [1.95 至 10.95]），但采用减压活动的儿童报告生活质量较差（糖尿病总评分差异 -4.19，95% CI [-8.35 至 -0.04]）。父母报告使用“其他补充剂”的儿童生活质量较低（核心总分差异 -6.26，95% CI [-11.29 至 -1.24]；核心心理社会差异为 -5.92，95% CI [-11.65 至 -0.19]）。
CAM 饮食与糖尿病青少年生活质量提高相关，而补充剂使用和减压活动与生活质量下降相关。CAM 使用与生活质量之间的时间顺序需要进一步研究。
