Department of Pharmaceutical Technology, Medical University of Gdansk, Gdansk, Poland.
J Eur Acad Dermatol Venereol. 2010 Aug;24(8):875-80. doi: 10.1111/j.1468-3083.2010.03588.x. Epub 2010 Feb 17.
A thorough examination of the skin is essential to screen various diseases accurately, evaluate the effectiveness of topically applied drugs and assess the results of dermatological surgeries such as skin grafts. The assessment of skin properties is also crucial in the cosmetics industry, where it is important to evaluate the effects skin care products have on these properties. The simplest and most widely used method of skin evaluation, the 'naked eye' assessment, enables researchers to assess only the skin surface and involves a large amount of inter-observer variability. Thanks to a great progress that has been made in physics, electronics and computer engineering in recent years, sophisticated imaging methods are increasingly available in day-to-day studies. The aim of this review was to present one of these techniques, namely the magnetic resonance imaging (MRI), and to discuss its possible use in skin examination and analysis. We present basic principles of MRI, as well as several interesting applications in the field of dermatology, and discuss the advantages and limitations of this method.
对皮肤进行全面检查对于准确筛查各种疾病、评估局部应用药物的效果以及评估皮肤移植等皮肤科手术的结果至关重要。在化妆品行业中，评估皮肤特性也非常重要，因为需要评估护肤品对这些特性的影响。皮肤评估最简单、最广泛使用的方法是“肉眼”评估，它只能评估皮肤表面，并且涉及大量的观察者间变异性。近年来，物理学、电子学和计算机工程领域取得了巨大进展，使得复杂的成像方法在日常研究中越来越普及。本综述的目的是介绍其中一种技术，即磁共振成像（MRI），并讨论其在皮肤检查和分析中的可能用途。我们介绍了 MRI 的基本原理，以及在皮肤科领域的一些有趣应用，并讨论了该方法的优缺点。
