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菲律宾裔加拿大女性不良妊娠结局的风险因素升高。

Elevated risk factors for adverse pregnancy outcomes among Filipina-Canadian women.

作者信息

Fuller-Thomson Esme, Rotermann Michelle, Ray Joel G

机构信息

Factor-Inwentash Faculty of Social Work, Department of Family and Community Medicine, University of Toronto, Toronto ON.

Health Analysis Division, Statistics Canada, Ottawa ON.

出版信息

J Obstet Gynaecol Can. 2010 Feb;32(2):113-119. doi: 10.1016/S1701-2163(16)34424-3.

Abstract

OBJECTIVES

Filipina immigrant women have higher than expected rates of preeclampsia and perinatal morbidity. Since obesity, diabetes mellitus (DM), and chronic hypertension are established risk factors for adverse pregnancy outcomes, we sought to determine whether they are more prevalent among Filipina women than other East Asian and Caucasian women.

METHODS

We pooled data from the 2000-01, 2003, 2005, and 2007 cycles of the nationally administered Canadian Community Health Survey. We generated data representative of 115,842 Filipina, 394,357 other East Asian, and 5,812 851 Caucasian women aged 18 to 49 years and living in Canada. Crude and adjusted odds ratios and 95% confidence intervals expressed the association between ethnicity and the risk of overweight (BMI >or= 25.0 kg/m(2)), obesity (BMI >or= 30.0 kg/m(2)), DM, and chronic hypertension.

RESULTS

The respective rates of obesity were approximately 5% for Filipinas, 2% for other East Asian women, and 14% for Caucasian women. The adjusted OR of obesity was 0.28 (95% CI 0.16 to 0.47) among Filipina women and 0.14 (95% CI 0.10 to 0.20) among other East Asians. The risk of DM was not significantly lower in Filipina women or other East Asian women than in Caucasians. Relative to a rate of 4.8% among Caucasians, chronic hypertension was significantly more prevalent among Filipinas (7.1%; adjusted OR 2.14, 95% CI 1.51 to 3.03), but not other East Asians (3.9%; adjusted OR 1.27, 95% CI 0.96 to 1.70). Post-hoc analyses showed that Filipina women were more likely to be hypertensive (adjusted OR 1.79, 95% CI 1.12 to 2.85) than other East Asian women; for obesity the adjusted OR was 1.88 (95% CI 0.97 to 3.66), and for DM it was 1.62 (95% CI 0.65 to 4.02).

CONCLUSION

Filipina women have higher than expected rates of excess weight and chronic hypertension, underlining the need to consider Filipina and other East Asian women separately.

摘要

目的

菲律宾移民女性的子痫前期和围产期发病率高于预期。由于肥胖、糖尿病(DM)和慢性高血压是不良妊娠结局的既定风险因素,我们试图确定这些因素在菲律宾女性中是否比其他东亚和白人女性更普遍。

方法

我们汇总了2000 - 01年、2003年、2005年和2007年全国性的加拿大社区健康调查的数据。我们生成了代表115842名年龄在18至49岁且居住在加拿大的菲律宾女性、394357名其他东亚女性和5812851名白人女性的数据。粗比值比和调整后的比值比以及95%置信区间表示种族与超重(体重指数[BMI]≥25.0 kg/m²)、肥胖(BMI≥30.0 kg/m²)、DM和慢性高血压风险之间的关联。

结果

菲律宾女性、其他东亚女性和白人女性的肥胖率分别约为5%、2%和14%。菲律宾女性中肥胖的调整后比值比为0.28(95%置信区间为0.16至0.47),其他东亚女性中为0.14(95%置信区间为0.10至0.20)。菲律宾女性和其他东亚女性患DM的风险并不显著低于白人女性。相对于白人女性4.8%的发病率,慢性高血压在菲律宾女性中更为普遍(7.1%;调整后比值比为2.14,95%置信区间为1.51至3.03),但在其他东亚女性中并非如此(3.9%;调整后比值比为1.27,95%置信区间为0.96至1.70)。事后分析表明,菲律宾女性比其他东亚女性更易患高血压(调整后比值比为1.79,95%置信区间为1.12至2.8);肥胖的调整后比值比为1.88(95%置信区间为0.97至3.66),DM的调整后比值比为1.62(95%置信区间为0.65至4.02)。

结论

菲律宾女性超重和慢性高血压的发生率高于预期,这凸显了将菲律宾女性和其他东亚女性分别考虑的必要性。

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