Jiang Ying, Chen Yue, Mao Yang
Surveillance and Risk Assessment Division, Center for Chronic Disease Prevention and Control, Public Health Agency of Canada, 120 Colonnade Road, Ottawa, Ontario, Canada.
Public Health. 2008 Mar;122(3):271-6. doi: 10.1016/j.puhe.2007.06.002. Epub 2007 Oct 10.
To determine the contribution of excess weight to prevalent diabetes based on data from a representative Canadian population.
This analysis was based on data from 72,627 subjects aged 20-64 years who participated in the Canadian Community Health Survey 2000-2001. Diabetes, body weight and height were self-reported. Stratified analysis and multivariate logistic regression models were conducted to adjust for confounding factors. Population attributable risk (PAR) was calculated.
Approximately half of the respondents were either overweight (33.4%) or obese (15.7%). The prevalence of diabetes was 3.4% for men and 2.9% for women, compared with 7.2% and 9.1% for obese men and women in the study. After adjusting for age, physical activity and income, the multiple logistic regression models showed that the odds ratios for diabetes associated with overweight and obesity were 1.8 [95% confidence intervals (CI) 1.4-2.2] and 3.6 (95% CI 2.9-4.5), respectively, for men, and 2.0 (95% CI 1.6-2.6) and 5.9 (95% CI 4.7-7.4) for women. The respective PARs were 18.7% and 25.5% for men, and 14.7% and 38.0% for women.
Approximately 50% of diabetes risk is attributable to excess body weight in the Canadian population. This study suggests that control of body weight is the most important priority in diabetes prevention and control.
基于加拿大代表性人群的数据,确定超重对糖尿病流行的影响。
本分析基于参加2000 - 2001年加拿大社区健康调查的72627名20 - 64岁受试者的数据。糖尿病、体重和身高均为自我报告。进行分层分析和多变量逻辑回归模型以调整混杂因素。计算人群归因风险(PAR)。
约一半的受访者超重(33.4%)或肥胖(15.7%)。男性糖尿病患病率为3.4%,女性为2.9%,而研究中肥胖男性和女性的患病率分别为7.2%和9.1%。在调整年龄、身体活动和收入后,多变量逻辑回归模型显示,男性超重和肥胖与糖尿病相关的比值比分别为1.8 [95%置信区间(CI)1.4 - 2.2]和3.6(95% CI 2.9 - 4.5),女性分别为2.0(95% CI 1.6 - 2.6)和5.9(95% CI 4.7 - 7.4)。男性的PAR分别为18.7%和25.5%,女性分别为14.7%和38.0%。
在加拿大人群中,约50%的糖尿病风险可归因于超重。本研究表明,控制体重是糖尿病预防和控制中最重要的优先事项。