Department of Natural Products for Chemical Genetic Research, Key Laboratory of Brain Functional Genomics, Ministry of Education, East China Normal University, Shanghai, PR China.
Phytochemistry. 2010 Apr;71(5-6):682-7. doi: 10.1016/j.phytochem.2009.12.016. Epub 2010 Feb 22.
Thirty-six naturally occurring compounds, including four C(10)-acetylenic glycosides and a lignan, were isolated from the whole plants of Saussurea cordifolia. Their structures were elucidated by means of spectroscopic and chemical methods to be 4,6-decadiyne-1-O-beta-D-apiofuranosyl-(1-->6)-beta-D-glucopyranoside (1), 4,6-decadiyne-1-O-alpha-L-rhamnopyranosyl-(1-->6)-beta-D-glucopyranoside (2), (8E)-decaene-4, 6-diyn-1-O-alpha-L-rhamnopyranosyl-(1-->6)-beta-D-glucopyranoside (3), (8Z)-decaene-4,6-diyn-1-O-beta-D-apiofuranosyl-(1-->6)-beta-D-glucopyranoside (4), and (2R,3S,4S)-4-(4-hydroxy-3-methoxybenzyl)-2-(5-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-tetrahydrofuran-3-ol (5).
从藏药麻花艽全草中分离得到 36 个天然产物，包括 4 个 C(10)-炔基糖苷和一个木脂素。通过波谱和化学方法鉴定它们的结构分别为：4,6-癸二炔-1-O-β-D-吡喃阿戊糖苷基-(1→6)-β-D-吡喃葡萄糖苷（1）、4,6-癸二炔-1-O-α-L-鼠李吡喃糖苷基-(1→6)-β-D-吡喃葡萄糖苷（2）、(8E)-癸-4,6-二炔-1-O-α-L-鼠李吡喃糖苷基-(1→6)-β-D-吡喃葡萄糖苷（3）、(8Z)-癸-4,6-二炔-1-O-β-D-吡喃阿戊糖苷基-(1→6)-β-D-吡喃葡萄糖苷（4）和(2R,3S,4S)-4-(4-羟基-3-甲氧基苄基)-2-(5-羟基-3-甲氧基苯基)-3-(羟甲基)四氢呋喃-3-醇（5）。
