College of Bioengineering, Dalian University, Dalian, China.
Fitoterapia. 2011 Apr;82(3):481-4. doi: 10.1016/j.fitote.2010.12.009. Epub 2011 Jan 8.
Studies on the chemical constituents of leaves of Camellia oleifera Abel. led to the isolation of 3 new bibenzyl glycosides. Their structures have been elucidated as 1-(3',5'-dihydroxy)phenyl-2-(4″-O-β-D-glucopyranosyl)phenylethane (1), 1-(3',5'-dimethoxy)phenyl-2-(4″-O-β-D-glucopyranosyl)phenylethane (2) and 1-(3',5'-dimethoxy)phenyl-2-[4″-O-β-D-glucopyranosyl(6→1)-O-α-L-rhamnopyranosyl]phenylethane (3) through spectral studies including HR-ESI-MS, ((1))H NMR, ((13))C NMR and 2D NMR experiments. All the above 3 bibenzyl glycosides showed cytotoxic activities to Hela and hep2 cell lines.
对油茶叶子的化学成分研究导致了 3 种新的二苄基糖苷的分离。通过光谱研究,包括高分辨电喷雾电离质谱(HR-ESI-MS)、((1))H NMR、((13))C NMR 和 2D NMR 实验,确定了它们的结构分别为 1-(3',5'-二羟基)苯基-2-(4″-O-β-D-吡喃葡萄糖基)苯乙烷(1)、1-(3',5'-二甲氧基)苯基-2-(4″-O-β-D-吡喃葡萄糖基)苯乙烷(2)和 1-(3',5'-二甲氧基)苯基-2-[4″-O-β-D-吡喃葡萄糖基(6→1)-O-α-L-鼠李吡喃糖基]苯乙烷(3)。以上 3 种二苄基糖苷均对 Hela 和 hep2 细胞系表现出细胞毒性活性。