National Centre for Biomedical Engineering Science, National University of Ireland, Galway, Ireland.
Biomaterials. 2010 May;31(14):3755-61. doi: 10.1016/j.biomaterials.2010.01.146. Epub 2010 Feb 23.
The desire to reduce the strut thickness of cardiovascular stents has driven the development of a new high strength radiopaque alloy, based on additions of platinum to a chromium-rich iron based matrix. This paper reports on initial development of the alloy and the rationale for selection of the composition. Data is presented for tensile and microstructural characterization, surface oxide analysis, corrosion resistance and endothelial cell response of the alloy. The results demonstrate the solid solution strengthening effect of the platinum, with an average yield strength of 480 MPa achieved. The material surface consists of primarily chromium oxide which contributes to the high corrosion resistance observed. The cell assay result suggests that surfaces of this Pt-enhanced alloy endothelialize in a manner comparable to stainless steel.
为了减少心血管支架的支柱厚度，人们开发了一种新的高强度放射线可检测合金，该合金是在富含铬的铁基基体中添加铂制成的。本文介绍了该合金的初步开发情况以及选择该成分的基本原理。本文提供了合金的拉伸和微观结构特性、表面氧化物分析、耐腐蚀性和内皮细胞反应的数据。结果表明，铂的固溶强化效果明显，平均屈服强度达到 480MPa。材料表面主要由氧化铬组成，这也是观察到的高耐腐蚀性的原因。细胞分析结果表明，这种增强铂的合金表面具有类似于不锈钢的内皮化方式。
