青年急性脑梗死的死亡率——十年经验

Mortality in acute cerebral infarction in young adults--a ten-year experience.

作者信息

Biller J, Adams H P, Bruno A, Love B B, Marsh E E

机构信息

Department of Neurology, University of Iowa College of Medicine, Iowa City.

出版信息

Angiology. 1991 Mar;42(3):224-30. doi: 10.1177/000331979104200307.

DOI:10.1177/000331979104200307

PMID:2018244

Abstract

We reviewed the one-month mortality among 213 patients aged fifteen to forty-five years (mean thirty-five) with acute cerebral infarction (CI) evaluated during the period July 1, 1977, to February 1, 1988. Atherosclerotic cerebral infarction (ACI) was diagnosed in 59 (27.7%) patients, 53 (24.9%) had non-atherosclerotic vasculopathies (NAV); 46 (21.6%) had cardioembolic infarcts (CEI). Hematologically related disorders were diagnosed in 30 (14.1%) patients; the cause of CI could not be established in 25 (11.7%) patients. Fourteen patients (9 men, 5 women, mean age 34.8 years), (6.6%) died within thirty days of their CI: 7 had CEI (7/46,15.2%); 4 had ACI (4/59, 6.7%); and 3 had NAV (3/53, 5.6%). Our data suggest that young patients with acute CI have a thirty-day mortality rate lower than older patients. Deaths were most common in patients with CEI. Brain edema and herniation accounted for 6 (43%) of the deaths.

摘要

我们回顾了1977年7月1日至1988年2月1日期间评估的213例年龄在15至45岁（平均35岁）的急性脑梗死（CI）患者的1个月死亡率。59例（27.7%）患者被诊断为动脉粥样硬化性脑梗死（ACI），53例（24.9%）患有非动脉粥样硬化性血管病（NAV）；46例（21.6%）患有心源性栓塞性梗死（CEI）。30例（14.1%）患者被诊断为血液学相关疾病；25例（11.7%）患者的CI病因无法确定。14例患者（9例男性，5例女性，平均年龄34.8岁）（6.6%）在CI发病后30天内死亡：7例患有CEI（7/46，15.2%）；4例患有ACI（4/59，6.7%）；3例患有NAV（3/53，5.6%）。我们的数据表明，急性CI的年轻患者30天死亡率低于老年患者。死亡在CEI患者中最为常见。脑水肿和脑疝占死亡病例的6例（43%）。