多发性硬化急性加重期的管理。
Management of acute exacerbations in multiple sclerosis.
作者信息
Ontaneda Daniel, Rae-Grant Alex D
机构信息
Neurological Institute, Cleveland Clinic, Cleveland, Ohio, 44195 USA.
出版信息
Ann Indian Acad Neurol. 2009 Oct;12(4):264-72. doi: 10.4103/0972-2327.58283.
Abstract
A key component of multiple sclerosis is the occurrence of episodes of clinical worsening with either new symptoms or an increase in older symptoms over a few days or weeks. These are known as exacerbations of multiple sclerosis. In this review, we summarize the pathophysiology and treatment of exacerbations and describe how they are related to the overall management of this disease.
摘要
多发性硬化症的一个关键组成部分是在几天或几周内出现临床症状恶化的发作，伴有新症状或原有症状加重。这些被称为多发性硬化症的发作。在本综述中，我们总结了发作的病理生理学和治疗方法，并描述了它们与该疾病整体管理的关系。
相似文献
1
Management of acute exacerbations in multiple sclerosis.多发性硬化急性加重期的管理。
Ann Indian Acad Neurol. 2009 Oct;12(4):264-72. doi: 10.4103/0972-2327.58283.
2
Self reported stressful life events and exacerbations in multiple sclerosis: prospective study.自我报告的压力性生活事件与多发性硬化症的病情加重：前瞻性研究
BMJ. 2003 Sep 20;327(7416):646. doi: 10.1136/bmj.327.7416.646.
3
[Therapeutic indications for acute episodes of multiple sclerosis].[多发性硬化急性发作的治疗指征]
Rev Neurol (Paris). 2001 Sep;157(8-9 Pt 2):988-95.
4
Oral versus intravenous steroids for treatment of relapses in multiple sclerosis.口服与静脉注射类固醇治疗多发性硬化症复发的比较
Cochrane Database Syst Rev. 2012 Dec 12;12:CD006921. doi: 10.1002/14651858.CD006921.pub3.
5
Acute Multiple Sclerosis Relapse.急性多发性硬化症复发
Continuum (Minneap Minn). 2016 Jun;22(3):799-814. doi: 10.1212/CON.0000000000000330.
6
Practical management problems of chronic obstructive pulmonary disease in the elderly: acute exacerbations.老年人慢性阻塞性肺疾病的实际管理问题：急性加重。
Curr Opin Pulm Med. 2011 Dec;17 Suppl 1:S49-54. doi: 10.1097/01.mcp.0000410748.28582.22.
7
[Influence of acute aggravations on the development of long-term handicap in relapsing remitting multiple sclerosis: a clinical study in 99 patients].[急性加重对复发缓解型多发性硬化症长期残疾发展的影响：99例患者的临床研究]
Rev Neurol (Paris). 2007 Jan;163(1):72-81. doi: 10.1016/s0035-3787(07)90357-4.
8
Oral versus intravenous steroids for treatment of relapses in multiple sclerosis.口服与静脉注射类固醇治疗多发性硬化症复发的疗效比较
Cochrane Database Syst Rev. 2009 Jul 8(3):CD006921. doi: 10.1002/14651858.CD006921.pub2.
9
Consequences of Insurance Denials Among U.S. Patients Prescribed Repository Corticotropin Injection for Acute Exacerbations of Multiple Sclerosis.美国为多发性硬化症急性加重期患者开具促肾上腺皮质激素注射液时保险拒付的后果
Neurol Ther. 2021 Jun;10(1):149-167. doi: 10.1007/s40120-020-00219-y. Epub 2020 Nov 10.
10
Repository corticotropin injection in multiple sclerosis: an update.储存型促肾上腺皮质激素注射液治疗多发性硬化症：最新进展
Neurodegener Dis Manag. 2018 Aug;8(4):217-225. doi: 10.2217/nmt-2018-0008. Epub 2018 Jun 5.
引用本文的文献
1
Potential Application of Plant-Derived Compounds in Multiple Sclerosis Management.植物源化合物在多发性硬化症治疗中的潜在应用。
Nutrients. 2024 Sep 5;16(17):2996. doi: 10.3390/nu16172996.
2
Patterns of multiple sclerosis presentation to the emergency department.多发性硬化症患者前往急诊科就诊的模式。
Front Neurol. 2024 Apr 26;15:1395822. doi: 10.3389/fneur.2024.1395822. eCollection 2024.
3
Tumefactive multiple sclerosis.瘤样多发性硬化症
Proc (Bayl Univ Med Cent). 2024 Feb 8;37(2):344-347. doi: 10.1080/08998280.2023.2289301. eCollection 2024.
4
Multiple Sclerosis-A Demyelinating Disorder and Its Dental Considerations-A Literature Review with Own Case Report.多发性硬化症——一种脱髓鞘疾病及其牙科相关考量——一篇文献综述及病例报告
Brain Sci. 2023 Jun 29;13(7):1009. doi: 10.3390/brainsci13071009.
5
Current Updates on the Diagnosis and Management of Multiple Sclerosis for the General Neurologist.普通神经科医生对多发性硬化症诊断与治疗的最新进展
J Clin Neurol. 2023 May;19(3):217-229. doi: 10.3988/jcn.2022.0208.
6
Immunomodulatory Aspects of Therapeutic Plasma Exchange in Neurological Disorders-A Pilot Study.免疫调节在神经障碍治疗性血浆置换中的作用：一项初步研究。
Int J Mol Sci. 2023 Mar 31;24(7):6552. doi: 10.3390/ijms24076552.
7
Immunoadsorption versus double-dose methylprednisolone in refractory multiple sclerosis relapses.免疫吸附与大剂量甲基强的松龙治疗难治性多发性硬化复发的疗效比较
J Neuroinflammation. 2022 Sep 7;19(1):220. doi: 10.1186/s12974-022-02583-y.
8
Predictors of progression from a first demyelinating event to clinically definite multiple sclerosis.首次脱髓鞘事件进展为临床确诊多发性硬化症的预测因素。
Brain Commun. 2022 Jul 9;4(4):fcac181. doi: 10.1093/braincomms/fcac181. eCollection 2022.
9
Current Utilization and Research Status of Traditional East Asian Herbal Medicine Treatment for Multiple Sclerosis: A Scoping Review.东亚传统草药治疗多发性硬化症的当前应用与研究现状：一项范围综述
Front Neurol. 2021 Oct 18;12:710769. doi: 10.3389/fneur.2021.710769. eCollection 2021.
10
Amnion-Derived Multipotent Progenitor Cells Suppress Experimental Optic Neuritis and Myelitis.羊膜衍生多能祖细胞抑制实验性视神经炎和脊髓炎。
Neurotherapeutics. 2021 Jan;18(1):448-459. doi: 10.1007/s13311-020-00949-9. Epub 2020 Oct 16.
本文引用的文献
1
Safety of liquid intravenous immunoglobulin for neuroimmunologic disorders in the home setting: a retrospective analysis of 1085 infusions.家庭环境中静脉注射液体免疫球蛋白治疗神经免疫性疾病的安全性：1085次输注的回顾性分析
J Clin Neuromuscul Dis. 2008 Dec;10(2):52-5. doi: 10.1097/CND.0b013e31818b2aef.
2
Multiple sclerosis.多发性硬化症
Lancet. 2008 Oct 25;372(9648):1502-17. doi: 10.1016/S0140-6736(08)61620-7.
3
EFNS guidelines for the use of intravenous immunoglobulin in treatment of neurological diseases: EFNS task force on the use of intravenous immunoglobulin in treatment of neurological diseases.欧洲神经病学学会（EFNS）关于静脉注射免疫球蛋白治疗神经疾病的指南：欧洲神经病学学会静脉注射免疫球蛋白治疗神经疾病特别工作组
Eur J Neurol. 2008 Sep;15(9):893-908. doi: 10.1111/j.1468-1331.2008.02246.x.
4
B cells and multiple sclerosis.B细胞与多发性硬化症
Lancet Neurol. 2008 Sep;7(9):852-8. doi: 10.1016/S1474-4422(08)70192-3.
5
Oral prednisone taper following intravenous steroids fails to improve disability or recovery from relapses in multiple sclerosis.在多发性硬化症中，静脉注射类固醇后逐渐减少口服泼尼松并不能改善残疾状况或复发后的恢复情况。
Eur J Neurol. 2008 Jul;15(7):677-80. doi: 10.1111/j.1468-1331.2008.02146.x. Epub 2008 May 6.
6
Corticosteroids for multiple sclerosis: I. Application for treating exacerbations.用于治疗多发性硬化症的皮质类固醇：I. 治疗病情加重的应用。
Neurotherapeutics. 2007 Oct;4(4):618-26. doi: 10.1016/j.nurt.2007.07.008.
7
Plasma exchange therapy for steroid-refractory superimposed relapses in secondary progressive multiple sclerosis.血浆置换疗法用于继发进展型多发性硬化症中对类固醇难治的叠加复发情况。
J Neurol. 2007 Sep;254(9):1288-9. doi: 10.1007/s00415-006-0497-0. Epub 2007 Aug 16.
8
Natalizumab for multiple sclerosis.那他珠单抗用于治疗多发性硬化症。
N Engl J Med. 2007 Jun 21;356(25):2622-9. doi: 10.1056/NEJMct071462.
9
Myelin regeneration in demyelinating disorders: new developments in biology and clinical pathology.脱髓鞘疾病中的髓鞘再生：生物学与临床病理学的新进展
Curr Opin Neurol. 2007 Jun;20(3):294-8. doi: 10.1097/WCO.0b013e32813aee7f.
10
The incomplete nature of multiple sclerosis relapse resolution.多发性硬化症复发缓解的不完全性。
J Neurol Sci. 2007 May 15;256 Suppl 1:S14-8. doi: 10.1016/j.jns.2007.01.062. Epub 2007 Mar 2.
Zotero 插件