Ontaneda Daniel, Rae-Grant Alex D
Neurological Institute, Cleveland Clinic, Cleveland, Ohio, 44195 USA.
Ann Indian Acad Neurol. 2009 Oct;12(4):264-72. doi: 10.4103/0972-2327.58283.
A key component of multiple sclerosis is the occurrence of episodes of clinical worsening with either new symptoms or an increase in older symptoms over a few days or weeks. These are known as exacerbations of multiple sclerosis. In this review, we summarize the pathophysiology and treatment of exacerbations and describe how they are related to the overall management of this disease.
多发性硬化症的一个关键组成部分是在几天或几周内出现临床症状恶化的发作,伴有新症状或原有症状加重。这些被称为多发性硬化症的发作。在本综述中,我们总结了发作的病理生理学和治疗方法,并描述了它们与该疾病整体管理的关系。