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头颈癌:爱荷华大学的发病率、治疗模式及生存率分析

Head and neck cancer: an analysis of the incidence, patterns of treatment, and survival at the University of Iowa.

作者信息

Hussey D H, Latourette H B, Panje W R

机构信息

Department of Radiology, University of Iowa College of Medicine, Iowa City.

出版信息

Ann Otol Rhinol Laryngol Suppl. 1991 Apr;152:2-16. doi: 10.1177/00034894911000s401.

Abstract

A retrospective study was performed with use of tumor registry data to evaluate tumor population characteristics, the patterns of care, and patient survival in 4,506 patients with head and neck cancers seen at The University of Iowa Hospitals and Clinics between 1960 and 1985. The total number of patients with head and neck cancers seen per year and the distribution by anatomic site remained relatively stable over the 26-year period. However, there was a general trend toward more advanced stages in later years. The selection of a treatment modality for this patient population correlated well with the site and stage of the disease and with the treatment philosophy of the managing physicians. Patient survival rates correlated well with the site and stage of the disease. There was a gradual improvement in 5-year survival rates over the 26-year period, from approximately 39% in 1960 to approximately 47% in 1984. This was principally due to an improvement in the 5-year survival rate for patients with "regional stage" disease, from approximately 22% in 1960 to approximately 41% in 1985.

摘要

我们利用肿瘤登记数据进行了一项回顾性研究,以评估1960年至1985年间在爱荷华大学医院及诊所就诊的4506例头颈癌患者的肿瘤人群特征、治疗模式及患者生存率。在这26年期间,每年头颈癌患者的总数以及按解剖部位的分布相对稳定。然而,在随后几年中存在疾病分期越来越晚的总体趋势。针对该患者群体治疗方式的选择与疾病的部位和分期以及主治医生的治疗理念密切相关。患者生存率与疾病的部位和分期密切相关。在这26年期间,5年生存率逐渐提高,从1960年的约39%提高到1984年的约47%。这主要归因于“区域分期”疾病患者的5年生存率有所提高,从1960年的约22%提高到1985年的约41%。

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