Department of Food Engineering, Hitit University, Corum, Turkey.
J Environ Sci Health B. 2009 Jun;44(5):472-80. doi: 10.1080/03601230902935154.
In the present study, we aimed at determining the release of aflatoxin B(1) (AFB(1)) and ochratoxin A (OTA) from different food products in the gastro-intestinal tract in the absence and presence of probiotics, a possible adsorbent. The average bioaccessibility of AFB(1) and OTA without probiotics was about 90%, and 30%, respectively, depending on several factors, such as food product, contamination level, compound and type of contamination (spiked versus naturally contaminated). The six probiotic bacteria showed varying binding capacity to AFB(1) and OTA depending on the bacterial strain, toxin studied, type of food and contamination level. A reduction to a maximum of 37% and 73% as observed for the bioaccessibility of AFB(1) and OTA in the presence of probiotic bacteria, respectively. This is the first report on the effect of probiotic bacteria on reducing the fraction of mycotoxins available for absorption in the gastrointestinal tract from different food products.
在本研究中，我们旨在确定黄曲霉毒素 B(1) (AFB(1))和赭曲霉毒素 A (OTA)在胃肠道中从不同食品中释放的情况，同时考虑了益生菌（一种可能的吸附剂）的存在与否。在没有益生菌的情况下，AFB(1)和 OTA 的平均生物可及性分别约为 90%和 30%，这取决于多种因素，如食品、污染水平、化合物和污染类型（添加的与天然污染的）。六种益生菌对 AFB(1)和 OTA 的结合能力因细菌株、研究的毒素、食品类型和污染水平而异。在添加益生菌的情况下，分别观察到 AFB(1)和 OTA 的生物可及性降低了 37%和 73%。这是关于益生菌细菌对减少胃肠道中不同食品中可吸收的霉菌毒素部分的第一个报告。
