Department of Pathology, University of Agriculture, Faisalabad-38040, Pakistan.
J Sci Food Agric. 2012 May;92(7):1540-4. doi: 10.1002/jsfa.4740. Epub 2011 Dec 16.
Mycotoxins, the secondary fungal metabolites, are unavoidable contaminants of human and animal food and feeds. The objectives of this study were to evaluate the effect of concurrent feeding of ochratoxin A (OTA) and aflatoxin B(1) (AFB(1) ) to breeder hens, upon their deposition in different tissues and eggs.
Residues of OTA and AFB(1) in (ng g(-1) ) were significantly higher in liver followed by kidneys and breast muscles by 22.54 ± 1.48, 4.22 ± 0.93 and 0.56 ± 0.06 for OTA (group fed OTA at 5 mg kg(-1) diet) and 1.44 ± 0.21, 0.25 ± 0.01 and 0.03 ± 0.01 for AFB(1) (group fed AFB(1) at 5 mg kg(-1) diet), respectively. Residues of OTA and AFB(1) in eggs appeared at days 3 and 5 of toxin feeding and disappeared at days 5 and 6 of withdrawal of mycotoxins contaminated feed, respectively. The residues of OTA and AFB(1) were significantly lower in the tissues of hens fed these toxins concurrently compared with the groups fed OTA and AFB(1) independently.
Residues of OTA and AFB(1) appeared in the tissues and eggs of laying hens kept on OTA- and AFB(1) -contaminated diets. Concurrent feeding of OTA and AFB(1) to hens significantly decreased the concentration of OTA and AFB(1) residues in the tissues and eggs.
真菌次生代谢产物霉菌毒素是人和动物食物及饲料中不可避免的污染物。本研究旨在评估同时给种母鸡饲喂赭曲霉毒素 A（OTA）和黄曲霉毒素 B1（AFB1）对其在不同组织和蛋中的沉积的影响。
OTA 和 AFB1 在肝脏中的残留量（ng/g）最高，分别为 22.54±1.48 和 4.22±0.93（OTA 组，饲料中 OTA 浓度为 5mg/kg），其次是肾脏和胸肌，分别为 0.56±0.06 和 0.25±0.01（OTA 组）；肝脏中 OTA 和 AFB1 的残留量（ng/g）分别为 1.44±0.21 和 0.03±0.01（AFB1 组，饲料中 AFB1 浓度为 5mg/kg），其次是肾脏和胸肌，分别为 0.25±0.01 和 0.01±0.01（AFB1 组）。OTA 和 AFB1 残留在毒素喂养第 3 天和第 5 天出现在鸡蛋中，并在停止摄入受霉菌毒素污染的饲料后的第 5 天和第 6 天消失。同时饲喂 OTA 和 AFB1 的母鸡组织中的 OTA 和 AFB1 残留量明显低于单独饲喂 OTA 和 AFB1 的组。
OTA 和 AFB1 残留在产蛋母鸡的组织和鸡蛋中，这些母鸡的饲料中含有 OTA 和 AFB1。同时给母鸡饲喂 OTA 和 AFB1 可显著降低组织和鸡蛋中 OTA 和 AFB1 残留量。
