Department of Internal Medicine and Public Health, Section of Occupational Medicine B. Ramazzini, University of Bari, Bari, Italy.
Int J Environ Health Res. 2009 Oct;19(5):369-77. doi: 10.1080/09603120903079349.
This study was designed to evaluate the influence of occupational and non-occupational factors on urinary arsenic excretion in workers exposed to iAs (inorganic arsenic) in the dismantlement of a factory which once produced fertilisers. We measured iAs and its methylated metabolites in 108 urinary samples of workers exposed to iAs in July 2006. A total of 13.9% of the samples showed levels higher than the Biological Exposure Index (BEI) of 35 microg/l (mean value 23.9 microg/l). After the improvement of working conditions, in August-October 2006 we collected urinary samples from each of the 108 workers enrolled. We also administrated a questionnaire, in order to investigate the influence of occupational and non-occupational factors on the urinary arsenic excretion. A significant difference was observed in relation with seafood consumption and age stratification. We have found a significant reduction of urinary arsenic excretion between the two phases of biological monitoring, probably due to appropriate hygiene work-related interventions.
本研究旨在评估职业和非职业因素对接触无机砷（iAs）的工人尿液中砷排泄的影响。我们测量了 2006 年 7 月在一家曾生产肥料的工厂拆除期间接触 iAs 的 108 名工人的尿液中的 iAs 及其甲基化代谢物。13.9%的样本显示出高于生物暴露指数（BEI）35μg/l（平均值 23.9μg/l）的水平。在改善工作条件后，2006 年 8 月至 10 月，我们从每个参与的 108 名工人中收集了尿液样本。我们还进行了问卷调查，以调查职业和非职业因素对尿液砷排泄的影响。与海鲜消费和年龄分层有关，观察到了显著差异。我们发现两次生物监测之间的尿液砷排泄量有显著减少，这可能是由于适当的与卫生相关的工作干预。
