阿肖罗定，一种从细叶阿福花中提取的具有强大脂氧合酶抑制作用的三萜二糖苷。

Asphorodin, a potent lipoxygenase inhibitory triterpene diglycoside from Asphodelus tenuifolius.

作者信息

Safder Muhammad, Imran Muhammad, Mehmood Rashad, Malik Abdul, Afza Nighat, Iqbal Lubna, Latif Mehreen

机构信息

International Centre for Chemical and Biological Sciences, HEJ Research Institute of Chemistry, University of Karachi, Karachi, Pakistan.

出版信息

J Asian Nat Prod Res. 2009 Nov;11(11):945-50. doi: 10.1080/10286020903214197.

DOI:10.1080/10286020903214197

PMID:20183258

Abstract

Asphorodin (1), a new diglycoside, has been isolated from the ethyl acetate-soluble fraction of Asphodelus tenuifolius. It showed significant inhibitory activity against the enzyme lipoxygenase in a concentration-dependent manner. The Lineweaver-Burk and Dixon plots indicated that the nature of inhibition was non-competitive.

摘要

阿斯霍罗定（1），一种新的二糖苷，已从细叶水仙的乙酸乙酯可溶部分中分离出来。它对脂氧合酶显示出显著的浓度依赖性抑制活性。Lineweaver-Burk和Dixon图表明抑制性质为非竞争性。