School of Pharmaceutical Sciences, University of Shizuoka, Yada 52-1, Suruga-ku, Shizuoka 422-8526, Japan.
J Nat Prod. 2010 Apr 23;73(4):609-12. doi: 10.1021/np900752t.
Chemical investigation of the aerial parts of Cimicifuga simplex afforded four new fukinolic acid analogues, cimicifugic acids K-N (1-4), and 10 known compounds, and C. japonica afforded three new fukinolic acid analogues, cimicifugic acids K-M (1-3), a new phenolic glycoside, shomaside F (5), and 10 known compounds. Cimicifugic acids K-N showed more potent hyaluronidase inhibitory activities than rosmarinic acid.
对升麻属植物 Cimicifuga simplex 的地上部分进行的化学成分研究得到了四个新的羽扇豆酸类似物，即 cimicifugic 酸 K-N（1-4），以及 10 种已知化合物；C. japonica 得到了三个新的羽扇豆酸类似物，即 cimicifugic 酸 K-M（1-3）、一个新的酚糖苷 shomaside F（5）和 10 种已知化合物。Cimicifugic 酸 K-N 比迷迭香酸具有更强的透明质酸酶抑制活性。
