School of Pharmaceutical Sciences, University of Shizuoka, Yada 52-1, Suruga-ku, Shizuoka 422-8526, Japan.
J Nat Prod. 2010 Apr 23;73(4):573-8. doi: 10.1021/np900675n.
From the 80% acetone extract of "Cimicifugae Rhizoma" (a mixture of Cimicifuga dahurica and C. heracleifolia used medicinally), seven new fukiic acid derivatives (1-7) and a new phenylethanoid derivative (8) were isolated along with eight known compounds (9-16). Fukinolic acid (9) and cimicifugic acids A-J (10-16, 5-7) showed stronger hyaluronidase inhibitory activities than the positive control, rosmarinic acid.
从“升麻根茎”（药用的升麻属植物升麻和兴安升麻的混合物）的 80%丙酮提取物中，分离得到了七种新的羽扇豆酸衍生物（1-7）和一种新的苯乙醇酸衍生物（8），以及八种已知化合物（9-16）。羽扇豆酸（9）和升麻酸 A-J（10-16，5-7）比阳性对照迷迭香酸具有更强的透明质酸酶抑制活性。
