Hospital of Korean Medicine, Kyung Hee University Medical Center, Seoul, South Korea.
BJOG. 2010 Apr;117(5):509-21. doi: 10.1111/j.1471-0528.2010.02489.x. Epub 2010 Feb 17.
The effectiveness of acupuncture in primary dysmenorrhoea is not fully understood.
To assess the effectiveness of acupuncture for the symptomatic treatment of primary dysmenorrhoea from randomised controlled trials (RCTs).
Nineteen electronic databases, including English, Korean, Japanese and Chinese databases, were systematically searched for RCTs investigating acupuncture for primary dysmenorrhoea up to July 2008 with no language restrictions.
All RCTs that evaluated the effects of acupuncture compared with controls were included. Studies that assessed the effect of moxibustion or body acupressure were excluded.
The study abstraction and quality assessment of all studies were undertaken following the detailed descriptions of these categories as described in the Cochrane Handbook for Systematic Reviews of Interventions.
Twenty-seven RCTs were systematically reviewed. Only nine of the 27 trials clearly described their methods of randomisation and none of the trials stated the methods of allocation concealment. Compared with pharmacological treatment or herbal medicine, acupuncture was associated with a significant reduction in pain. Three studies reported reduced pain within groups from baseline; however, two RCTs did not find a significant difference between acupuncture and sham acupuncture.
AUTHOR'S CONCLUSIONS: The review found promising evidence in the form of RCTs for the use of acupuncture in the treatment of primary dysmenorrhoea compared with pharmacological treatment or herbal medicine. However, the results were limited by methodological flaws. The evidence for the effectiveness of acupuncture for the treatment of primary dysmenorrhoea is not convincing compared with sham acupuncture. Further rigorous nonpenetrating placebo-controlled RCTs are warranted.
针刺治疗原发性痛经的疗效尚不完全清楚。
评估针刺治疗原发性痛经的随机对照试验(RCT)的疗效。
系统检索了 19 个电子数据库,包括英文、韩文、日文和中文数据库,检索时间截至 2008 年 7 月,无语言限制,检索对象为针刺治疗原发性痛经的 RCT。
所有评估针刺与对照组疗效的 RCT 均纳入。排除艾灸或体压按摩效果评估的研究。
根据《Cochrane 干预系统评价手册》的详细说明,对所有研究的研究提取和质量评估进行了分类。
系统性综述共纳入 27 项 RCT。27 项试验中只有 9 项明确描述了随机分组方法,没有一项试验报告了分配隐藏方法。与药物治疗或草药治疗相比,针刺治疗原发性痛经疼痛的缓解更为显著。有 3 项研究报告了组内疼痛从基线下降,但 2 项 RCT 未发现针刺与假针刺之间存在显著差异。
该综述以 RCT 的形式为针刺治疗原发性痛经提供了有前景的证据,与药物治疗或草药治疗相比,针刺治疗原发性痛经更有效。然而,由于方法学上的缺陷,结果受到限制。与假针刺相比,针刺治疗原发性痛经的有效性证据尚不令人信服。需要进一步进行严格的非穿透性安慰剂对照 RCT。