Institute of Legal Medicine, Catholic University, School of Medicine, Rome, Italy.
Diagn Pathol. 2010 Feb 25;5:15. doi: 10.1186/1746-1596-5-15.
We report a rare case of ostial plication as a potential cause of sudden death. Very few reports and images are available in the specialized literature regarding this anomaly. Ostial plication may be a source of sudden death or cause of death when no other significant autopsy findings are present.Ostial plication is a congenital severe obstruction/occlusion of the right or left ostium. Plication of the aortic wall leads to a "valve-like" ridge that can act as a door blocking inflow during diastolic filling, with consequent ischemia and a potentially life-threatening arrhythmia. The true incidence of this condition and its relationship to sudden death have not been reported in the literature. We believe that this case will be useful to autopsy pathologists in detecting this infrequent anomaly, thus providing a more accurate estimation of its incidence.
我们报告了一例罕见的瓣口褶作为猝死的潜在原因。关于这种异常，专业文献中只有很少的报道和图像。当没有其他明显的尸检发现时，瓣口褶可能是猝死或死亡的原因。瓣口褶是右或左瓣口的先天性严重阻塞/闭塞。主动脉壁的褶叠导致“瓣状”嵴，可在舒张期充盈时充当阻挡流入的门，导致缺血和潜在的危及生命的心律失常。这种情况的真实发生率及其与猝死的关系尚未在文献中报道。我们相信，这个病例对于尸检病理学家检测这种罕见的异常将是有用的，从而更准确地估计其发生率。
