Department of Bioscience and Biotechnology, Konkuk University, Seoul, South Korea.
Appl Microbiol Biotechnol. 2010 Apr;86(4):1017-25. doi: 10.1007/s00253-010-2496-4. Epub 2010 Feb 26.
Erythritol, a four-carbon polyol, is a biological sweetener with applications in food and pharmaceutical industries. It is also used as a functional sugar substitute in special foods for people with diabetes and obesity because of its unique nutritional properties. Erythritol is produced by microbial methods using mostly osmophilic yeasts and has been produced commercially using mutant strains of Aureobasidium sp. and Pseudozyma tsukubaensis. Due to the high yield and productivity in the industrial scale of production, erythritol serves as an inexpensive starting material for the production of other sugars. This review focuses on the approaches for the efficient erythritol production, strategies used to enhance erythritol productivity in microbes, and the potential biotechnological applications of erythritol.
赤藓糖醇，一种四碳多元醇，是一种具有生物甜味剂的应用在食品和制药行业。它也被用作特殊食品中的功能性糖替代品，适用于糖尿病和肥胖人群，因为它具有独特的营养特性。赤藓糖醇主要通过耐渗酵母等微生物方法生产，并且已经使用深黄被孢霉和异常威克汉姆酵母的突变株在工业规模上商业化生产。由于在工业生产规模上具有高得率和生产力，赤藓糖醇可用作生产其他糖的廉价起始原料。本文综述了高效生产赤藓糖醇的方法、提高微生物中赤藓糖醇生产力的策略，以及赤藓糖醇的潜在生物技术应用。
