Sińczuk-Walczak Halina
Instytut Medycyny Pracy im. prof, J. Nofera, Łódź Przychodnia Chorób Zawodowych.
Med Pr. 2009;60(6):519-22.
This paper presents a review of the effect of arsenic (As) and its inorganic compounds on the nervous system. In humans, inhalation exposure mostly occurs in occupational conditions. In the occupational environment, the most extensive exposure to this element is observed in the copper industry. Chronic As poisoning is manifested by skin and mucous membrane lesions, impairment of the nervous system in the form of disorders of psychic functions and polyneuropathies, retrobulbar neuritis, disorders of peripheral circulation and the risk for Raynaud's syndrome. Arsenic-induced polyneuropathy is usually a very serious and chronic disease. A complete recovery is observed in only 15-20% of patients. As-induced encephalopathy is an irreversible process.
本文综述了砷（As）及其无机化合物对神经系统的影响。在人类中，吸入暴露主要发生在职业环境中。在职业环境中，铜行业对该元素的暴露最为广泛。慢性砷中毒表现为皮肤和黏膜损伤、以精神功能障碍和多发性神经病形式出现的神经系统损害、球后视神经炎、外周循环障碍以及雷诺综合征风险。砷中毒性多发性神经病通常是一种非常严重的慢性疾病。仅15% - 20%的患者能完全康复。砷中毒性脑病是一个不可逆的过程。
