Rabago David, Slattengren Andrew, Zgierska Aleksandra
Department of Family Medicine, University of Wisconsin School of Medicine and Public Health, 777 South Mills Street, Madison, WI 53715, USA.
Prim Care. 2010 Mar;37(1):65-80. doi: 10.1016/j.pop.2009.09.013.
Prolotherapy is an injection-based complementary and alternative medical therapy for chronic musculoskeletal pain. Prolotherapy techniques and injected solutions vary by condition, clinical severity, and practitioner preferences; over several treatment sessions, a fairly small volume of an irritant or sclerosing solution is injected at sites on painful ligament and tendon insertions and in adjacent joint space during several treatment sessions. Prolotherapy is becoming increasingly popular in the United States and internationally and is actively used in clinical practice. Prolotherapy has been assessed as a treatment for various painful chronic musculoskeletal conditions that are refractory to "standard of care" therapies. Although anecdotal clinical success guides the use of prolotherapy for many conditions, clinical trial literature supporting evidence-based decision-making for the use of prolotherapy exists for low back pain, several tendinopathies, and osteoarthritis.
注射疗法是一种用于治疗慢性肌肉骨骼疼痛的基于注射的补充和替代医学疗法。注射疗法的技术和注射溶液因病情、临床严重程度和从业者偏好而异；在几个治疗疗程中，会在疼痛的韧带和肌腱附着点以及相邻关节间隙的部位注射少量刺激性或硬化性溶液。注射疗法在美国和国际上越来越受欢迎，并在临床实践中得到积极应用。注射疗法已被评估为治疗各种对“标准护理”疗法难治的疼痛性慢性肌肉骨骼疾病的方法。尽管轶事临床成功指导了注射疗法在许多病症中的应用，但存在支持基于证据决策使用注射疗法治疗腰痛、几种肌腱病和骨关节炎的临床试验文献。
