Ophidism and Scorpionism Research Program, University of Antioquia, Medellín, Colombia.
Ultrason Sonochem. 2010 Jun;17(5):756-9. doi: 10.1016/j.ultsonch.2010.01.014. Epub 2010 Feb 6.
This study evaluates the favorable effects of using ultrasound during the dissolution process of ethanolic extracts of Heliconia psittacorum and Heliconia rostrata (Heliconiaceae), a family of plants reported to have antiophidic activities. The extracts were subjected to an ultrasound treatment before incubation with venom, and carbohydrate and protein contents were calculated. The ultrasound-treated extracts delayed the clotting effect of venom by up to 45.59 s compared to the positive control (venom). The metabolites content increased to 296.6% and 61.6% in protein and carbohydrate content, respectively. Ultrasound increases the amount of primary and secondary metabolites (potentially antiophidics) released from the extract into the media, and thereby enhances the anticoagulant activity of these plants against the Bothrops asper (mapaná X) venom.
本研究评估了在 Heliconia psittacorum 和 Heliconia rostrata（Heliconiaceae）乙醇提取物的溶解过程中使用超声的有利效果，Heliconia psittacorum 和 Heliconia rostrata 是具有抗蛇毒活性的植物科。提取物在与毒液孵育之前进行了超声处理，并计算了碳水化合物和蛋白质含量。与阳性对照（毒液）相比，超声处理的提取物将凝血作用延迟了长达 45.59 秒。蛋白质和碳水化合物含量的代谢物含量分别增加到 296.6%和 61.6%。超声增加了从提取物中释放到介质中的初级和次级代谢物（潜在抗蛇毒）的量，从而增强了这些植物对 Bothrops asper（mapaná X）毒液的抗凝活性。
