Letnansky K, Dostal V, Reiss-Gutfreund R J
Osterr Z Onkol. 1977 Oct 20;4(2-3):39-41.
The phosphorylation of histones of the F1 group and of fraction F2a2 is stimulated in monkey kidney cells (CV-1) to almost two times the control values 14 hours after their infection with herpes virus, type 2. At the same time high amounts of viral DNA are produced. It seems very likely that the stimulated phosphorylation of these histone fractions is a prerequisite for the enhanced synthesis of DNA and possibly also RNA.
在猴肾细胞(CV-1)中,感染2型疱疹病毒14小时后,F1组组蛋白和F2a2组分的磷酸化被刺激至几乎是对照值的两倍。与此同时,产生了大量的病毒DNA。这些组蛋白组分磷酸化受到刺激很可能是DNA以及可能还有RNA合成增强的一个先决条件。