Protein synthesis in pig kidney cells infected with herpes simplex virus type 1.

Two polypeptides of apparent mol. mass 87,000 and 35,000 were identified in pig kidney cells infected with herpes simplex virus type 1 (HSV-1) after reversing the cycloheximide block. The synthesis of the polypeptide 87,000 declined from 22 hr post infection (p.i.). Its production was prevented by actinomycin D added to the infected cells after removal of cycloheximide. Evidence is presented that the polypeptide 35,000 may be of the cellular origin.