由新型猪源甲型流感病毒（H1N1）引起的伴有肺泡出血的急性肺损伤
Acute lung injury with alveolar hemorrhage due to a novel swine-origin influenza A (H1N1) virus.
作者信息
Yokoyama Toshiki, Tsushima Kenji, Ushiki Atsuhito, Kobayashi Nobumitsu, Urushihata Kazuhisa, Koizumi Tomonobu, Kubo Keishi
机构信息
The First Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto.
出版信息
Intern Med. 2010;49(5):427-30. doi: 10.2169/internalmedicine.49.3022. Epub 2010 Mar 1.
A 40-year-old woman with no major medical illness except for morbid obesity (BMI 40.7) was admitted to our hospital because of bilateral pneumonia due to a novel swine-origin influenza A (H1N1) virus (S-OIV). Non-invasive ventilation was introduced because of the hypoxemia. The description of bronchoalveolar lavage fluid findings showed an alveolar hemorrhage and neutrophilic inflammation. No evidence of bacterial infection was found. She was treated with oseltamivir and sivelestat sodium, neutrophil elastase inhibitor and thereafter was successfully discharged from the hospital. This case is the first report of a patient with acute lung injury with an alveolar hemorrhage caused by the S-OIV.
一名40岁女性，除病态肥胖（BMI 40.7）外无其他重大疾病，因新型甲型H1N1流感病毒（S-OIV）导致的双侧肺炎入住我院。因低氧血症采用无创通气。支气管肺泡灌洗 fluid findings 的描述显示有肺泡出血和中性粒细胞炎症。未发现细菌感染证据。给予其奥司他韦和西维来司他钠（一种中性粒细胞弹性蛋白酶抑制剂）治疗，之后成功出院。该病例是首例关于由S-OIV引起急性肺损伤伴肺泡出血患者的报告。 （注：原文中“bronchoalveolar lavage fluid findings”表述不太准确，推测可能是“bronchoalveolar lavage fluid findings”，翻译为“支气管肺泡灌洗结果” ）
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