Department of Surgery, Breast Unit, Catholic University, Rome, Italy.
Med Sci Monit. 2010 Mar;16(3):CS33-39.
Adenoid cystic carcinoma of the breast is a rare neoplasm accounting for 0.1% of all malignant breast tumors and presenting most commonly as a painful breast mass. Compared with the more common histological forms of breast cancer, it has a more favorable prognosis and lymph node involvement or distant metastases seldom occur.
A unique case of multifocal adenoid cystic carcinoma of the breast presenting as a painful and well-defined lump and treated with conservative surgery with adjuvant radiotherapy is reported.
There is no consensus on the optimal management of this disease. A breast-conserving approach may be recommended even if mastectomy has been traditionally the treatment of choice. Chemotherapy, radiation, and hormonal therapy have been infrequently used and so far have had no defined role in this kind of neoplasm. The authors found no other reports in the literature focusing on a conservative approach to multifocal adenoid cystic carcinoma.
乳腺腺样囊性癌是一种罕见的肿瘤，占所有恶性乳腺肿瘤的 0.1%，最常见的表现为疼痛性乳腺肿块。与更为常见的乳腺癌组织学类型相比，它的预后较好，淋巴结受累或远处转移很少发生。
报告了一例罕见的乳腺多灶性腺样囊性癌病例，表现为疼痛性且界限清楚的肿块，采用保守手术联合辅助放疗治疗。
对于这种疾病，目前尚无最佳治疗方法的共识。即使传统上选择乳房切除术，也可以推荐采用保乳治疗方法。化疗、放疗和激素治疗很少使用，到目前为止，在这种肿瘤类型中没有明确的作用。作者在文献中没有发现其他关注多灶性腺样囊性癌保守治疗方法的报道。
