Departments of Bacteriology and Plant Pathology, University of Wisconsin-Madison, WI 53706, USA.
Nat Rev Microbiol. 2010 Apr;8(4):251-9. doi: 10.1038/nrmicro2312. Epub 2010 Mar 1.
Antibiotic-resistant pathogens are profoundly important to human health, but the environmental reservoirs of resistance determinants are poorly understood. The origins of antibiotic resistance in the environment is relevant to human health because of the increasing importance of zoonotic diseases as well as the need for predicting emerging resistant pathogens. This Review explores the presence and spread of antibiotic resistance in non-agricultural, non-clinical environments and demonstrates the need for more intensive investigation on this subject.
耐药病原体对人类健康至关重要，但人们对耐药决定因素的环境储存库知之甚少。环境中抗生素耐药性的起源与人类健康有关，因为人畜共患病的重要性日益增加，以及需要预测新出现的耐药病原体。本综述探讨了非农业、非临床环境中抗生素耐药性的存在和传播，并表明需要对此主题进行更深入的研究。
