Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Via Bologna 148, 10154, Torino, Italy.
Environ Monit Assess. 2020 Mar 16;192(4):238. doi: 10.1007/s10661-020-8191-8.
The potential threat of both metals and antibiotics to the environment and human health has raised significant concerns in the last decade. Metal-resistant and antibiotic-resistant bacteria are found in most environments, including water, and the risk posed to humans and animals due to the spread of antibiotic-resistant bacteria and antibiotic-resistant genes in the environment is increasing. Bacteria have developed the ability to tolerate metals even at notable concentrations. This ability tends to favor the selection of antibiotic-resistant strains, even in pristine water environments, with the potential risk of spreading this resistance to human pathogens. In this mini-review, we focus on investigations performed in marine and freshwater environments worldwide, highlighting the presence of co-resistance to metals and antibiotics.
在过去的十年中,金属和抗生素对环境和人类健康的潜在威胁引起了人们的高度关注。在包括水在内的大多数环境中都存在耐药和抗抗生素的细菌,由于环境中抗生素耐药细菌和抗生素耐药基因的传播,对人类和动物构成的风险正在增加。细菌已经发展出耐受金属的能力,即使在显著浓度下也能耐受。这种能力往往有利于选择抗生素耐药菌株,即使在原始的水生态环境中也是如此,这有可能将这种耐药性传播给人类病原体。在这个小型综述中,我们重点研究了全球海洋和淡水环境中的调查结果,强调了金属和抗生素的共同耐药性的存在。