普氏原羚自然发生的硫诱导铜缺乏症的研究。
Studies of a naturally occurring sulfur-induced copper deficiency in Przewalski's gazelles.
作者信息
Zhou LiYe, Long RiJun, Pu XiuYing, Qi Juan, Zhang WeiWei
机构信息
Department of Grassland Science, Gansu Agricultural University, Lanzhou 730070, China.
出版信息
Can Vet J. 2009 Dec;50(12):1269-72.
The Przewalski's gazelles in the Hudong area of the Qinghai Lake area in China were affected by an ailment characterized by pica, emaciation, dyskinesia, loss of appetite, and anemia. Concentrations of copper (Cu) in soil and forage from affected and unaffected areas were similar and within the normal range, but concentrations of sulfur (S) in soil and forage were significantly higher (P < 0.01) in affected than in unaffected areas. Concentrations of Cu in blood, hair, and liver from the affected Przewalski's gazelles were significantly lower (P < 0.01) than those in healthy animals. Affected Przewalski's gazelles showed a hypochromic microcytic anemia and a low level of ceruloplasmin. Oral administration of copper sulphate (CuSO(4)) prevented and cured the disease. We conclude that the disorder of Przewalski's gazelles was caused by secondary Cu deficiency, mainly due to high S content in forage.
中国青海湖地区湖东区域的普氏原羚受到一种病症的影响，其特征为异食癖、消瘦、运动障碍、食欲不振和贫血。患病区域和未患病区域土壤及草料中的铜（Cu）浓度相似且在正常范围内，但患病区域土壤和草料中的硫（S）浓度显著高于未患病区域（P < 0.01）。患病普氏原羚血液、毛发和肝脏中的铜浓度显著低于健康动物（P < 0.01）。患病普氏原羚表现为低色素小细胞性贫血和血浆铜蓝蛋白水平较低。口服硫酸铜（CuSO₄）可预防和治愈该疾病。我们得出结论，普氏原羚的这种病症是由继发性铜缺乏引起的，主要原因是草料中硫含量过高。
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