Faculty of Chemistry, University of Wroclaw, 14 F. Joliot-Curie Street, Wroclaw, Poland.
J Pept Sci. 2010 Apr;16(4):186-9. doi: 10.1002/psc.1219.
The subject of these studies was synthesis and determination of biological properties of a series of insect peptides, such as alloferon, Any-GS and their analogues. The synthesis of 14 peptides was performed by the solid-phase method. Biological effect of these peptides was evaluated by the antiviral test against Human Herpes Virus type 1 (HHV-1) in vitro using a Vero cell line. It was found that the investigated peptides inhibit the replication of HHV-1 in Vero cells.
这些研究的主题是一系列昆虫肽，如 alloferon、Any-GS 及其类似物的合成和生物特性的测定。通过固相法合成了 14 种肽。通过使用 Vero 细胞系在体外对抗人类单纯疱疹病毒 1（HHV-1）的抗病毒试验评估了这些肽的生物学效应。结果发现，所研究的肽抑制了 HHV-1 在 Vero 细胞中的复制。
Zotero 插件