Faculty of Pharmaceutical Sciences, Hoshi University, Ebara 2-4-41 Shinagawa-ku, Tokyo 142-8501, Japan.
J Nat Prod. 2010 Apr 23;73(4):763-7. doi: 10.1021/np9007987.
Gneyulins A (1) and B (2), two new stilbene trimers consisting of oxyresveratrol constituent units, and noidesols A (3) and B (4), two new dihydroflavonol-C-glucosides, were isolated from the bark of Gnetum gnemonoides. The structures and configurations of 1-4 were elucidated on the basis of 2D NMR correlations and X-ray analysis. Gneyulins A (1) and B (2) showed inhibition of Na(+)-glucose transporters (SGLT-1 and SGLT-2).
从买麻藤科买麻藤属植物土木香 Gnetum gnemonoides 的树皮中分离得到两个新的苯乙烯三聚体 gneyulins A（1）和 B（2），它们由 oxyresveratrol 组成单元构成，以及两个新的二氢黄酮醇-C-葡萄糖苷 noidesols A（3）和 B（4）。基于 2D NMR 相关和 X 射线分析，确定了 1-4 的结构和构型。gneyulins A（1）和 B（2）显示出对 Na(+)-葡萄糖转运蛋白（SGLT-1 和 SGLT-2）的抑制作用。
